Platelet function and lipid-lowering interventions

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Milionis, H. J.
Elisaf, M. S.
Mikhailidis, D. P.

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peer-reviewed

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Platelets

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Platelets play an important role in the process of atherothrombosis, and antiplatelet therapy is of proven efficacy in the prevention of vascular events in high-risk patients. In this review, we briefly consider the studies reporting that circulating atherogenic lipoproteins enhance platelet activity. We also evaluate the evidence showing that lipid-lowering interventions (including the use of statins) are associated with the normalisation of platelet activity. This beneficial effect should enhance the anti-atherogenic and anti-thrombotic potential of lipid-lowering interventions.

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http://www.ncbi.nlm.nih.gov/pubmed/16801115
http://informahealthcare.com/doi/abs/10.1080/09537109975834

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en

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Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής

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