Vitamin D and parathormone levels of late-preterm formula fed infants during the first year of life
| dc.contributor.author | Giapros, V. I. | en |
| dc.contributor.author | Schiza, V. | en |
| dc.contributor.author | Challa, A. S. | en |
| dc.contributor.author | Cholevas, V. K. | en |
| dc.contributor.author | Theocharis, P. D. | en |
| dc.contributor.author | Kolios, G. | en |
| dc.contributor.author | Pantou, C. | en |
| dc.contributor.author | Andronikou, S. K. | en |
| dc.date.accessioned | 2015-11-24T19:41:45Z | |
| dc.date.available | 2015-11-24T19:41:45Z | |
| dc.identifier.issn | 1476-5640 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/24527 | |
| dc.rights | Default Licence | - |
| dc.title | Vitamin D and parathormone levels of late-preterm formula fed infants during the first year of life | en |
| heal.abstract | BACKGROUND/OBJECTIVES: Preterm infants are at risk for low vitamin D but documentation on late-preterm infants is sparse. This prospective study monitored longitudinally vitamin D and parathormone (PTH) levels in late-preterm formula fed infants during the first year of life, taking into consideration in utero and postnatal growth, and season and diet. SUBJECTS/METHODS: The study population comprised 128 infants of gestational age (GA) 32-36 weeks, of which 102 were appropriate (AGA) and the remaining 26 were small for GA (SGA). Serum levels of vitamin D (25(OH)D), PTH calcium, phosphate (P) and alkaline phosphate were estimated at 2 and 6 weeks, and at 3, 6, 9 and 12 months of age. RESULTS: The 25(OH)D levels were relatively low at 2 and 6 weeks in both AGA and SGA infants (21+/-11, 20+/-7 ng/ml and 25+/-16, 23+/-8 ng/ml, respectively), but increased at 6 months (45+/-14, 47+/-10 ng/ml) and remained stable thereafter. SGA infants had lower 25(OH)D levels at 9 and 12 months (AGA 45+/-14, 47+/-18 ng/ml vs SGA 38+/-13, 37+/-13 ng/ml, P<0.05). Deficiency of 25(OH)D (<20 ng/ml) was found in 18.5% of measurements in 92 (72%) infants, and its insufficiency (20-32 ng/ml) was found in 29.2% of measurements in 99 (77.3%) infants. Most measurements with vitamin D <32 ng/ml were observed at the first three study points, where PTH showed an inverse association with 25(OH)D, reaching a plateau thereafter. CONCLUSIONS: Late-preterm, formula fed infants may have suboptimal vitamin D levels and elevated PTH, especially, during the first 3 months. Those born SGA may have lower vitamin D levels up to the end of the first year of life. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1038/ejcn.2011.158 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/21897423 | - |
| heal.journalName | Eur J Clin Nutr | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2012 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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