Διαταραχές στους βιοχημικούς δείκτες του μεταβολισμού των οστών στη νεανική χρόνια αρθρίτιδα
| dc.contributor.author | Τζούφη, Μερόπη | el |
| dc.date.accessioned | 2015-10-13T06:41:02Z | |
| dc.date.available | 2015-10-13T06:41:02Z | |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/446 | |
| dc.identifier.uri | http://dx.doi.org/10.26268/heal.uoi.49 | |
| dc.rights | Default License | |
| dc.subject | Ασβεστιουρία | el |
| dc.subject | Βιοχημικοί δείκτες | el |
| dc.subject | Βιταμίνη D | el |
| dc.subject | Μεταβολισμός των οστών | el |
| dc.subject | Νεανική χρόνια αρθρίτιδα | el |
| dc.subject | Νεφρική επαναρρόφηση φωσφόρου | el |
| dc.subject | Οστεοκαλσίνη | el |
| dc.subject | Φώσφορος ορού | el |
| dc.title | Διαταραχές στους βιοχημικούς δείκτες του μεταβολισμού των οστών στη νεανική χρόνια αρθρίτιδα | el |
| heal.abstract | BIOCHEMICAL INDICES AND HORMONES RELATED TO BONE METABOLISM, WERE STUDIED IN 35 CHILDREN WITH J.C.A. THE MEAN AGE OF THEM WAS 8.1+/-4.1Y. AND THE MEAN DURATION OF THE DESEASE 2.4+/-2.0Y. PATIENTS WERE DIVIDED INTO THREE GROUPS, ACCORDING TO THE TYPE OF ONSET: SYSTEMIC(7), POLYARTICULAR(12) AND PAUCIARTICULAR(16). ALL WERE ON NSAIDS, WITH ADDITIONAL THERAPY OF GOLD INJECTIONS AND D-PENICILLAMIN, TO THE PATIENTS WITH POLYARTICULAR J.C.A. AND LOW DOSE STEROIDS (PREDNISONE<10MG /D) TO THE ONES WITH SYSTEMIC. TWO GROUPS OF SUBJECTS, WERE USED AS CONTROLS: ONE INCLUDED 17 HEALTHY CHILDREN AND THE OTHER, 8 CHILDREN WHO WERE ON CORTICOSTEROIDS FOR DIFFERENT REASONS. SERUM P AND TMP/GFR WERE FOUND SIGNIFICANTLY LOWER (4.0+/-0.9MG/DL AND 3.3+ /-0.56MG/DL GF) IN THE SYSTEMIC GROUP THAN IN CONTROLS (4.65+/-0.6, P<0.01 AND 4.2+/-0.56 MG/DL GF, P<0.05) AND THAN IN THE CONTROLS ON STEROIDS (4.8+ /-0.8MG/DL, P<0.01 AND 4.0+/-0.71MG/DL GF, P<0.05). IN THE SAME PATIENT GROUP LOWER CONCENTRATIONS THAN THE TWO CONTROL GROUPS WERE FOUND, FOR OSTEOCALCIN (5.5+/- 4.7 VS 11.0+/-4.5 AND 10.0+/-5.7NG/ML, P<0.05), 25OHD (15.6+ /-4.9 VS 27.3+/- 6.2 AND 20.6+/-9.8NG/ML, P<0.001), 1,25(OH)2D(12.1+ /-6.0 VS 20.9+/-11.0 AND 27.6+/-3.2PG/ML) AND ALP (58+/-16.4 VS 83+/-24.2 AND 80+/-15.6 IV/L, P<0.05). IN THE POLY- AND PAUCIARTICULAR JCA, THE 25OHD LEVELS, WERE FOUND LOWER, ABSTRACT TRANSACTED | en |
| heal.academicPublisher | Πανεπιστήμιο Ιωαννίνων Σχολή Ιατρικής Τμήμα Ιατρικής Τομέας Υγείας του Παιδιού | el |
| heal.academicPublisherID | uoi | |
| heal.access | free | |
| heal.advisorName | Λαπατσάνης, Πέτρος | el |
| heal.bibliographicCitation | Βιβλιογραφία: σ. 141-174 | el |
| heal.classification | Ρευματοειδής αρθρίτιδα στα παιδιά | el |
| heal.committeeMemberName | Λαπατσάνης, Πέτρος | el |
| heal.committeeMemberName | Μουτσόπουλος, Χαράλαμπος | el |
| heal.committeeMemberName | Παπαδοπούλου-Κουλούμπη, Ζωή | el |
| heal.committeeMemberName | Σεφεριάδης, Κωνσταντίνος | el |
| heal.committeeMemberName | Δρόσος, Αλέξανδρος | el |
| heal.committeeMemberName | Σιαμοπούλου-Μαυρίδου, Αντιγόνη | el |
| heal.committeeMemberName | Χάλλα, Άννα | el |
| heal.fullTextAvailability | false | |
| heal.identifier.secondary | http://thesis.ekt.gr/thesisBookReader/id/10969#page/1/mode/2up | |
| heal.language | el | |
| heal.numberOfPages | 174 σ. | |
| heal.publicationDate | 1998 | |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων Σχολή Ιατρικής Τμήμα Ιατρικής Τομέας Υγείας του Παιδιού | el |
| heal.type | doctoralThesis | |
| heal.type.el | Διδακτορική διατριβή | el |
| heal.type.en | Doctoral thesis | en |
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