Association of endothelial shear stress with plaque thickness in a real three-dimensional left main coronary artery bifurcation model
| dc.contributor.author | Papafaklis, M. I. | en |
| dc.contributor.author | Bourantas, C. V. | en |
| dc.contributor.author | Theodorakis, P. E. | en |
| dc.contributor.author | Katsouras, C. S. | en |
| dc.contributor.author | Fotiadis, D. I. | en |
| dc.contributor.author | Michalis, L. K. | en |
| dc.date.accessioned | 2015-11-24T17:32:12Z | |
| dc.date.available | 2015-11-24T17:32:12Z | |
| dc.identifier.issn | 0167-5273 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/13688 | |
| dc.rights | Default Licence | - |
| dc.subject | angiography | en |
| dc.subject | intravascular ultrasound | en |
| dc.subject | computational fluid dynamics | en |
| dc.subject | coronary bifurcation | en |
| dc.subject | shear stress | en |
| dc.subject | atherosclerosis | en |
| dc.subject | flow | en |
| dc.title | Association of endothelial shear stress with plaque thickness in a real three-dimensional left main coronary artery bifurcation model | en |
| heal.abstract | We report for the first time a real three-dimensional reconstruction of the left main coronary artery, left main bifurcation, left anterior descending coronary artery and left circumflex coronary artery using biplane angiography and intravascular ultrasound imaging in a patient with a proximal stenosis in the left anterior descending coronary artery. By using computational fluid dynamics in the three-dimensional luminal model we computed endothelial shear stress, while plaque thickness was calculated as the difference between the three-dimensional lumen and outer vessel wall; plaque thickness was found to be inversely related to endothelial shear stress in the left main coronary artery and bifurcation. The application of our methodology for real three-dimensional reconstruction of the left main coronary artery and bifurcation is useful for investigating the relationship of hemodynamic parameters with plaque thickness in this critical coronary region. (c) 2006 Elsevier Ireland Ltd. All rights reserved. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | DOI 10.1016/j.ijcard.2006.04.030 | - |
| heal.identifier.secondary | <Go to ISI>://000244512800033 | - |
| heal.identifier.secondary | http://ac.els-cdn.com/S0167527306003317/1-s2.0-S0167527306003317-main.pdf?_tid=d89d9cab2a84384b9d395136279c9001&acdnat=1339758344_3d81b9f55c96c0e23fa020335153ca40 | - |
| heal.journalName | Int J Cardiol | en |
| heal.journalType | peer reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2007 | - |
| heal.publisher | Elsevier | en |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Μηχανικών Επιστήμης Υλικών | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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