Haemodynamic and renal effects of tadalafil in patients with cirrhosis

dc.contributor.authorKalambokis, G. N.en
dc.contributor.authorKosta, P.en
dc.contributor.authorPappas, K.en
dc.contributor.authorTsianos, E. V.en
dc.date.accessioned2015-11-24T19:14:27Z
dc.date.available2015-11-24T19:14:27Z
dc.identifier.issn1007-9327-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/21312
dc.rightsDefault Licence-
dc.subjectCarbolines/adverse effects/*therapeutic useen
dc.subjectHemodynamics/*drug effectsen
dc.subjectHumansen
dc.subjectHypertension, Portal/*drug therapy/etiology/physiopathologyen
dc.subjectKidney/*drug effects/physiopathologyen
dc.subjectLiver Cirrhosis/complications/*drug therapy/physiopathologyen
dc.subjectNatriuresis/drug effectsen
dc.subjectPhosphodiesterase Inhibitors/adverse effects/*therapeutic useen
dc.subjectVasodilator Agents/adverse effects/*therapeutic useen
dc.titleHaemodynamic and renal effects of tadalafil in patients with cirrhosisen
heal.abstractA recent report introduced the phosphodiesterase-5 inhibition by vardenafil as a novel treatment of portal hypertension in patients with cirrhosis. In the herein presented "letter to the editor", the administration of tadalafil did not influence portal haemodynamics but impaired systemic haemodynamics in patients with cirrhosis. Our observations concur with the results of a report in a previous issue of World Journal of Gastroenterology (October 2008). Moreover, tadalafil adversely affected renal function in patients with decompensated liver disease.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/20954291-
heal.journalNameWorld J Gastroenterolen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2010-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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