SIADH and hyponatremia with theophylline

dc.contributor.authorLiberopoulos, E. N.en
dc.contributor.authorAlexandridis, G.en
dc.contributor.authorChristidis, D. S.en
dc.contributor.authorElisaf, M. S.en
dc.date.accessioned2015-11-24T18:51:40Z
dc.date.available2015-11-24T18:51:40Z
dc.identifier.issn1060-0280-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18289
dc.rightsDefault Licence-
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectHumansen
dc.subjectHyponatremia/*chemically induceden
dc.subjectInappropriate ADH Syndrome/*chemically induceden
dc.subjectMaleen
dc.subjectTheophylline/*adverse effectsen
dc.titleSIADH and hyponatremia with theophyllineen
heal.abstractOBJECTIVE: To report a case of possible theophylline-induced hyponatremia due to the syndrome of inappropriate antidiuretic hormone (SIADH). CASE SUMMARY: An 88-year-old man developed severe symptomatic hyponatremia (serum sodium 112 mEq/L) associated with inappropriate natriuresis (urinary sodium 58 mEq/L) temporally related to the initiation of theophylline. The patient fulfilled the criteria for the diagnosis of SIADH after all other causes of hyponatremia were excluded. Furthermore, no other drugs or conditions that could have evoked SIADH were found. DISCUSSION: Theophylline has rarely been associated with hyponatremia. A thiazide-like action of the drug on the stimulation of SIADH could be the underlying mechanism for SIADH. CONCLUSIONS: Theophylline should be considered as a possible cause of hyponatremia.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/12086552-
heal.journalNameAnn Pharmacotheren
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2002-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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