Synthesis and characterization of thermosensitive PNIPAM microgels covered with superparamagnetic gamma-Fe2O3 nanoparticles

dc.contributor.authorRubio-Retama, J.en
dc.contributor.authorZafeiropoulos, N. E.en
dc.contributor.authorSerafinelli, C.en
dc.contributor.authorRojas-Reyna, R.en
dc.contributor.authorVoit, B.en
dc.contributor.authorCabarcos, E. L.en
dc.contributor.authorStamm, M.en
dc.date.accessioned2015-11-24T17:39:06Z
dc.date.available2015-11-24T17:39:06Z
dc.identifier.issn0743-7463-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/14590
dc.rightsDefault Licence-
dc.subjectiron-oxide nanoparticlesen
dc.subjectn-isopropylacrylamideen
dc.subjectdrug-deliveryen
dc.subjectpoly(n-isopropylacrylamide)en
dc.subjectparticlesen
dc.subjectphen
dc.subjectpurificationen
dc.subjecttemperatureen
dc.subjectelectrolyteen
dc.subjectpolymersen
dc.titleSynthesis and characterization of thermosensitive PNIPAM microgels covered with superparamagnetic gamma-Fe2O3 nanoparticlesen
heal.abstractIn the present study we report a facile and reproducible method of preparing magnetic thermosensitive hybrid material based on P(NIPAM) microgels covered with gamma-Fe2O3 nanoparticles of 6-nm size. The iron oxide nanoparticles provided magnetic response to the microgels. In addition, the presence of the magnetic nanoparticles on the microgels altered their swelling behavior and shifted their volume phase transition temperature to higher values. In particular, for inorganic shells with 18% (w/w) of magnetic nanoparticles the volume phase transition of the microgels was shifted from 36 to 40 degrees C. In contrast, for shells consisting of 38% (w/w) magnetic nanoparticles the volume phase transition of the microgels was almost blocked, thus indicating that the microgel thermal response was strongly affected by the presence of the inorganic nanoparticles. The synthesized thermosensitive magnetic microgels are envisaged to be ideal for potential applications as thermosensitive targeted drug delivery systems.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primaryDoi 10.1021/La7009594-
heal.identifier.secondary<Go to ISI>://000249560100048-
heal.journalNameLangmuiren
heal.journalTypepeer reviewed-
heal.languageen-
heal.publicationDate2007-
heal.publisherAmerican Chemical Societyen
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Μηχανικών Επιστήμης Υλικώνel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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