Real-time PCR analysis of trinucleotide repeat allele expansions in the androgen receptor gene
| dc.contributor.author | Chatzikyriakidou, A. | en |
| dc.contributor.author | Yapijakis, C. | en |
| dc.contributor.author | Sofikitis, N. | en |
| dc.contributor.author | Vassilopoulos, D. | en |
| dc.contributor.author | Georgiou, I. | en |
| dc.date.accessioned | 2015-11-24T18:54:56Z | |
| dc.date.available | 2015-11-24T18:54:56Z | |
| dc.identifier.issn | 1084-8592 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/18777 | |
| dc.rights | Default Licence | - |
| dc.subject | Alleles | en |
| dc.subject | Chromosomes, Human, X | en |
| dc.subject | Female | en |
| dc.subject | Humans | en |
| dc.subject | Male | en |
| dc.subject | Muscular Disorders, Atrophic/genetics | en |
| dc.subject | Receptors, Androgen/*genetics | en |
| dc.subject | Transition Temperature | en |
| dc.subject | *Trinucleotide Repeat Expansion | en |
| dc.title | Real-time PCR analysis of trinucleotide repeat allele expansions in the androgen receptor gene | en |
| heal.abstract | INTRODUCTION: The expansion of specific trinucleotide repeats results in certain genetic disorders. METHOD: Real-time PCR analysis was used to rapidly discriminate between normal and expanded (CAG)(n) alleles in the androgen receptor gene. RESULT: The difference in melting temperature (T(m)) between the most common normal and expanded alleles was approximately 1 degrees C. CONCLUSION: Real-time PCR analysis seems to be a highly reliable and rapid method, which may facilitate the first molecular approach to human trinucleotide repeat disorders. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/16392902 | - |
| heal.journalName | Mol Diagn | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2005 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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