New prognostic markers for outcome of acute pancreatitis: overview of reporting in 184 studies
| dc.contributor.author | Sigounas, D. E. | en |
| dc.contributor.author | Tatsioni, A. | en |
| dc.contributor.author | Christodoulou, D. K. | en |
| dc.contributor.author | Tsianos, E. V. | en |
| dc.contributor.author | Ioannidis, J. P. | en |
| dc.date.accessioned | 2015-11-24T19:02:04Z | |
| dc.date.available | 2015-11-24T19:02:04Z | |
| dc.identifier.issn | 1536-4828 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/19760 | |
| dc.rights | Default Licence | - |
| dc.subject | Acute Disease | en |
| dc.subject | Biological Markers/*analysis | en |
| dc.subject | Humans | en |
| dc.subject | Outcome Assessment (Health Care)/methods | en |
| dc.subject | Pancreatitis/*diagnosis/*metabolism | en |
| dc.subject | Prognosis | en |
| dc.subject | Reproducibility of Results | en |
| dc.subject | Sensitivity and Specificity | en |
| dc.title | New prognostic markers for outcome of acute pancreatitis: overview of reporting in 184 studies | en |
| heal.abstract | OBJECTIVES: The objective of this study was to assess the reporting of studies on new prognostic markers of outcome in acute pancreatitis. METHODS: We used MEDLINE searches complemented with perusal of review articles' references to identify eligible English-language studies. We included studies evaluating nonroutine markers for acute pancreatitis. Eligible outcomes included Atlanta criteria, Japanese criteria for severity, multiple/single organ failure, complications, interventional treatment, hospitalization length, and death. We generated a 47-item checklist on Acute Pancreatitis Prognosis by adapting a previously constructed reporting guidance instrument for prognostic tumor markers (REMARK [Reporting Recommendations for Tumor Marker Prognostic Studies]). The checklist addresses the reporting of essential information in prognostic studies. RESULTS: The 184 identified eligible studies reported on 196 different prognostic markers. One hundred forty-four studies (78.3%) found at least 1 prognostic marker to be nominally statistically significant. Significant improvements over time were seen in the reporting for 17 items, but major deficiencies were noted even in 2004-2009 studies. Particularly, 12 items were reported in less than 10% of studies overall and even within the most recent studies. CONCLUSIONS: Despite some improvements over time, the reporting of important aspects of prognostic studies in acute pancreatitis remains suboptimal. The proposed REMARK-based checklist may help improve the quality and reporting of research in this field. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1097/MPA.0b013e31820bf8ac | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/21343832 | - |
| heal.journalName | Pancreas | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2011 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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