Phantom cytomegalovirus infection in vasculitis patients: what it means and what to do

dc.contributor.authorKatsanos, K. H.en
dc.contributor.authorKostoula, A.en
dc.contributor.authorKatopodis, K. P.en
dc.contributor.authorSiamopoulos, K. C.en
dc.date.accessioned2015-11-24T18:59:08Z
dc.date.available2015-11-24T18:59:08Z
dc.identifier.issn0172-8172-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19345
dc.rightsDefault Licence-
dc.subjectAntibodies, Viral/blooden
dc.subjectAntiviral Agents/therapeutic useen
dc.subjectCytomegalovirus/*immunology/isolation & purificationen
dc.subjectCytomegalovirus Infections/blood/complications/*drug therapyen
dc.subjectDNA, Viral/*blooden
dc.subjectGanciclovir/therapeutic useen
dc.subjectHumansen
dc.subjectImmunoglobulin Men
dc.subjectPolymerase Chain Reactionen
dc.subjectTreatment Outcomeen
dc.subjectVasculitis/*complications/drug therapyen
dc.titlePhantom cytomegalovirus infection in vasculitis patients: what it means and what to doen
heal.abstractWe report our experience and hypothesis on the diagnosis and treatment of patients with vasculitis who are simultaneously diagnosed with serum-positive cytomegalovirus (CMV) immunoglobulin (Ig)M antibodies and negative CMV DNA polymerase chain reaction (PCR). It remains unknown how to treat this kind of "phantom" CMV infection. In a patient diagnosed with Henoch-Schonlein vasculitis, CMV IgM titers were increased while angiitis and renal function deteriorated. Empiric treatment of phantom CMV infection with ganciclovir in this CMV IgM-positive and PCR-negative patient resulted in complete vasculitis remission, serum CMV antibody seroconversion, and renal function improvement. These results imply something more than coincidence.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1007/s00296-004-0522-5-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/15503030-
heal.identifier.secondaryhttp://www.springerlink.com/content/54lvgywkyxn74eqy/fulltext.pdf-
heal.journalNameRheumatol Inten
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2005-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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