Genetic abnormalities in oligodendroglial and ependymal tumours
| dc.contributor.author | Goussia, A. C. | en |
| dc.contributor.author | Kyritsis, A. P. | en |
| dc.contributor.author | Mitlianga, P. | en |
| dc.contributor.author | Bruner, J. M. | en |
| dc.date.accessioned | 2015-11-24T19:15:00Z | |
| dc.date.available | 2015-11-24T19:15:00Z | |
| dc.identifier.issn | 0340-5354 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/21434 | |
| dc.rights | Default Licence | - |
| dc.subject | Brain Neoplasms/*genetics/pathology | en |
| dc.subject | Chromosomes/genetics/ultrastructure | en |
| dc.subject | Ependymoma/*genetics/pathology | en |
| dc.subject | Humans | en |
| dc.subject | Oligodendroglioma/*genetics/pathology | en |
| dc.title | Genetic abnormalities in oligodendroglial and ependymal tumours | en |
| heal.abstract | Oligodendroglial and ependymal tumours are not the most common glial neoplasms; however, they are important subtypes of gliomas with different tumour biologies. Cytogenetic information has suggested that losses of chromosomes 1 p and 19 q are the most frequent genetic alterations in oligodendroglial tumours. Combined loss of these chromosomes has been associated with better chemotherapeutic response and prolonged overall survival. Loss of chromosome 22 is a well defined abnormality in ependymomas. In addition, deletion of chromosome 6 q may be another frequent chromosomic aberration in paediatric ependymomas. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/12013578 | - |
| heal.journalName | J Neurol | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2001 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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