Two types of nutritional rickets in infants

dc.contributor.authorLapatsanis, P.en
dc.contributor.authorMakaronis, G.en
dc.contributor.authorVretos, C.en
dc.contributor.authorDoxiadis, S.en
dc.date.accessioned2015-11-24T19:01:56Z
dc.date.available2015-11-24T19:01:56Z
dc.identifier.issn0002-9165-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19743
dc.rightsDefault Licence-
dc.subjectAge Factorsen
dc.subjectAlkaline Phosphatase/*blooden
dc.subjectCalcium/*blooden
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectHypocalcemia/complicationsen
dc.subjectInfanten
dc.subjectMaleen
dc.subjectPhosphorus/*blooden
dc.subjectPhosphorus Metabolism Disorders/complicationsen
dc.subjectRadius/radiographyen
dc.subject*Rickets/classification/complications/metabolism/radiographyen
dc.subjectSex Factorsen
dc.subjectUlna/radiographyen
dc.titleTwo types of nutritional rickets in infantsen
heal.abstractIn 100 infants with nutritional rickets, i.e., responsive to vitamin D therapy, we found a close inverse relationship between serum phosphorus, on the one hand, and serum alkaline phosphatase and the presence of radiological signs of rickets, on the other. There was no correlation between serum calcium and the severity of bone lesions. It is concluded that hypophosphatemia but not hypocalcemia is typical of rickets. Since hypophosphatemia and rickets can be produced experimentally by phosphate deficiency alone, we suggest our infants can be divided into two groups, one with true vitamin D deficiency that leads to hypocalcemia and no or mild bone lesions, and one with primary phosphate deficiency, resulting perhaps from a defect in phosphate transport, which leads to rickets and hypophosphatemia.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/998537-
heal.journalNameAm J Clin Nutren
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1976-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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