Increased levels of tumor markers in the follow-up of 400 patients with breast cancer without recurrence or metastasis: interpretation of false-positive results

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dc.contributor.authorZervoudis, S.en
dc.contributor.authorPeitsidis, P.en
dc.contributor.authorIatrakis, G.en
dc.contributor.authorPanourgias, E.en
dc.contributor.authorKoureas, A.en
dc.contributor.authorNavrozoglou, I.en
dc.contributor.authorDubois, J. B.en
dc.date.accessioned2015-11-24T19:10:46Z
dc.date.available2015-11-24T19:10:46Z
dc.identifier.issn1107-0625-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20867
dc.rightsDefault Licence-
dc.subjectBreast Neoplasms/*diagnosis/pathologyen
dc.subjectFalse Positive Reactionsen
dc.subjectFemaleen
dc.subjectFollow-Up Studiesen
dc.subjectHumansen
dc.subjectNeoplasm Metastasisen
dc.subjectNeoplasm Recurrence, Local/*diagnosisen
dc.subjectNeoplasm Stagingen
dc.subjectTumor Markers, Biological/*blooden
dc.titleIncreased levels of tumor markers in the follow-up of 400 patients with breast cancer without recurrence or metastasis: interpretation of false-positive resultsen
heal.abstractPURPOSE: To analyze, study and interpret the increased levels of tumor markers in breast cancer patients without recurrence or metastasis. PATIENTS AND METHODS: We studied a series of 400 patients with stage 1 breast cancer during a 3-year follow-up after primary treatment. Follow-up included frequent serum estimation of CEA, CA 15.3, CA 125, CA 27-29, TPA and TPS tumor markers. RESULTS: Of 358 patients being continuously disease-free, 18 (5%) cases showed false-positive levels of tumor markers, associated with benign conditions and not to cancer recurrence or metastasis. These conditions included ovarian cysts, thyroid disorders, hepatitis, renal stone and sarcoidosis. CONCLUSION: The value of increased tumor markers should be interpreted cautiously because it doesn't always imply disease recurrence. Tumor markers may increase in many benign conditions.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18067207-
heal.journalNameJ BUONen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2007-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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