Tamoxifen-induced severe hypertriglyceridemia and pancreatitis

dc.contributor.authorElisaf, M. S.en
dc.contributor.authorNakou, K.en
dc.contributor.authorLiamis, G.en
dc.contributor.authorPavlidis, N. A.en
dc.date.accessioned2015-11-24T19:43:05Z
dc.date.available2015-11-24T19:43:05Z
dc.identifier.issn0923-7534-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/24722
dc.rightsDefault Licence-
dc.subjectAntineoplastic Agents, Hormonal/*adverse effects/therapeutic useen
dc.subjectAntineoplastic Combined Chemotherapy Protocols/administration &en
dc.subjectdosage/therapeutic useen
dc.subjectBreast Neoplasms/*drug therapyen
dc.subjectCisplatin/administration & dosageen
dc.subjectFemaleen
dc.subjectFluorouracil/administration & dosageen
dc.subjectHumansen
dc.subjectHypertriglyceridemia/*chemically induceden
dc.subjectMethotrexate/administration & dosageen
dc.subjectMiddle Ageden
dc.subjectPancreatitis/*chemically induceden
dc.subjectTamoxifen/*adverse effects/therapeutic useen
dc.titleTamoxifen-induced severe hypertriglyceridemia and pancreatitisen
heal.abstractTamoxifen exhibits favorable effects on the lipid and lipoprotein profile since it decreases the total and LDL cholesterol levels as well as the Lp(a) levels. Additionally, a small increase in serum triglycerides is commonly found after tamoxifen administration. However, severe hypertriglyceridemia which can sometimes be associated with life-threatening complications is occasionally noticed. Herein, we describe a patient who developed tamoxifen-induced severe hypertriglyceridemia and pancreatitis. An analysis of the underlying pathogenetic mechanisms as well as a review of the relevant literature is also provided.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/11038048-
heal.identifier.secondaryhttp://annonc.oxfordjournals.org/content/11/8/1067.full.pdf-
heal.journalNameAnn Oncolen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2000-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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