Wnt signaling and neural stem cells: caught in the Wnt web

dc.contributor.authorMichaelidis, T. M.en
dc.contributor.authorLie, D. C. C.en
dc.date.accessioned2015-11-24T16:34:05Z
dc.date.available2015-11-24T16:34:05Z
dc.identifier.issn0302-766X-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/7753
dc.rightsDefault Licence-
dc.subjectsignalingen
dc.subjectwnten
dc.subjectstem cellen
dc.subjectneurogenesisen
dc.subjectdevelopmenten
dc.subjectterminal-binding-proteinen
dc.subjectcentral-nervous-systemen
dc.subjectnuclear beta-cateninen
dc.subjectadult dentate gyrusen
dc.subjectdorsal spinal-corden
dc.subjectnotch target genesen
dc.subjectwnt/beta-cateninen
dc.subjectneuronal differentiationen
dc.subjectprogenitor cellsen
dc.subjectin-ven
dc.titleWnt signaling and neural stem cells: caught in the Wnt weben
heal.abstractWnt proteins have now been identified as major physiological regulators of multiple aspects of stem cell biology, from self-renewal and pluripotency to precursor cell competence and terminal differentiation. Neural stem cells are the cellular building blocks of the developing nervous system and provide the basis for continued neurogenesis in the adult mammalian central nervous system. Here, we outline the most recent advances in the field about the critical factors and regulatory networks involved in Wnt signaling and discuss recent findings on how this increasingly intricate pathway contributes to the shaping of the developing and adult nervous system on the level of the neural stem cell.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primaryDOI 10.1007/s00441-007-0476-5-
heal.identifier.secondary<Go to ISI>://000251618500017-
heal.identifier.secondaryhttp://www.springerlink.com/content/m061132831k114l2/fulltext.pdf-
heal.journalNameCell Tissue Resen
heal.journalTypepeer reviewed-
heal.languageen-
heal.publicationDate2008-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών και Τεχνολογιών. Τμήμα Βιολογικών Εφαρμογών και Τεχνολογιώνel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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