Meta-analysis comparing drug-eluting stents with bare metal stents
| dc.contributor.author | Katritsis, D. G. | en |
| dc.contributor.author | Karvouni, E. | en |
| dc.contributor.author | Ioannidis, J. P. | en |
| dc.date.accessioned | 2015-11-24T19:04:47Z | |
| dc.date.available | 2015-11-24T19:04:47Z | |
| dc.identifier.issn | 0002-9149 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/20103 | |
| dc.rights | Default Licence | - |
| dc.subject | Chi-Square Distribution | en |
| dc.subject | Coated Materials, Biocompatible | en |
| dc.subject | Coronary Disease/*therapy | en |
| dc.subject | *Drug Implants | en |
| dc.subject | Humans | en |
| dc.subject | Paclitaxel/*administration & dosage | en |
| dc.subject | Randomized Controlled Trials as Topic | en |
| dc.subject | Sirolimus/*administration & dosage | en |
| dc.subject | *Stents | en |
| dc.title | Meta-analysis comparing drug-eluting stents with bare metal stents | en |
| heal.abstract | We performed a meta-analysis of 10 randomized trials of 5,066 patients with 6 to 12 months of follow-up. The summary risk differences excluded any major differences between the 2 types of stents for death (0.12%, 95% confidence interval [CI] -0.34% to 0.58%, p = 0.60) and overall myocardial infarction (0.04%, 95% CI -0.72% to 0.81%, p = 0.91). There was a modest increase in the risk of Q-wave myocardial infarction with drug-eluting stents (0.36%, 95% CI -0.04% to 0.77%, p = 0.080) but no difference in non-Q-wave myocardial infarction (-0.26%, 95% CI -0.95% to 0.43%, p = 0.47). The trend for increased risk of Q-wave myocardial infarction was seen for paclitaxel and sirolimus stents (risk differences 0.28% and 0.58%, respectively). Drug-eluting stents also had a nonsignificant trend for higher risk of thrombosis (0.29%, 95% CI -0.08% to 0.66%, p = 0.13). We conclude that sirolimus- and paclitaxel-eluting stents are equivalent to bare-metal stents in terms of mortality and overall myocardial infarction risk for the first year of follow-up; the meta-analysis excludes with considerable confidence the presence of large, clinically relevant differences for these outcomes. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1016/j.amjcard.2004.10.041 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/15721109 | - |
| heal.identifier.secondary | http://ac.els-cdn.com/S0002914904017886/1-s2.0-S0002914904017886-main.pdf?_tid=26f4a54dc1b76de550afb12508681ce3&acdnat=1333364353_02c61b7acd60636a095140207dc5757d | - |
| heal.journalName | Am J Cardiol | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2005 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
Αρχεία
Φάκελος/Πακέτο αδειών
1 - 1 of 1
Φόρτωση...
- Ονομα:
- license.txt
- Μέγεθος:
- 1.74 KB
- Μορφότυπο:
- Item-specific license agreed upon to submission
- Περιγραφή: