Thalamic volume measurement in normal fetuses using three-dimensional sonography
Loading...
Date
Authors
Sotiriadis, A.
Dimitrakopoulos, I.
Eleftheriades, M.
Agorastos, T.
Makrydimas, G.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Type
Type of the conference item
Journal type
peer-reviewed
Educational material type
Conference Name
Journal name
J Clin Ultrasound
Book name
Book series
Book edition
Alternative title / Subtitle
Description
PURPOSE.: Brain thalami are important for a wide range of sensorimotor and neuropsychiatric functions. This study was carried out to calculate normative values for thalami volume during fetal life. METHODS.: Fetal thalami volumes were measured using 3D ultrasound in 122 normal, singleton fetuses at 20(+0) -34(+6) weeks' gestation. Virtual Organ Computer-aided AnaLysis (VOCAL) was used to obtain a sequence of six sections of each thalamus, starting from the transthalamic view of the brain at an axial plane. Thalamic contour was drawn manually. Volume contrast imaging was used to enhance image quality when needed. The volume of the thalamus distal to the transducer was also measured by a second operator in 30 randomly selected cases, blind to the measurements of the first, to calculate interobserver agreement. RESULTS.: Thalamic volume increased with gestational age, following a quadratic equation (R(2) = 0.83). There was no significant difference in volume between the right and left thalamus. The mean volume of each thalamus increased from 0.45 ml at 20(+0) weeks, to 1.39 ml at 28(+0) weeks, to 2.17 ml at 34(+0) weeks. The 95% limits of interobserver agreement for thalamic volume were -14.3% to +17.2%. CONCLUSIONS.: The increase in thalamic volume with gestation can be described adequately by a quadratic equation. The moderate interobserver repeatability is attributed to the similar echogenicity between the thalamus and its surrounding structures. (c) 2012 Wiley Periodicals, Inc. J Clin Ultrasound, 2012.
Description
Keywords
Subject classification
Citation
Link
http://www.ncbi.nlm.nih.gov/pubmed/22286969
http://onlinelibrary.wiley.com/store/10.1002/jcu.21888/asset/21888_fta.pdf?v=1&t=h0l47ae1&s=e06f47de5b67d8beaefcc7666a66fcef40e7c3e3
http://onlinelibrary.wiley.com/store/10.1002/jcu.21888/asset/21888_fta.pdf?v=1&t=h0l47ae1&s=e06f47de5b67d8beaefcc7666a66fcef40e7c3e3
Language
en
Publishing department/division
Advisor name
Examining committee
General Description / Additional Comments
Institution and School/Department of submitter
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής