Treatment of the pregnant mother with cancer: a systematic review on the use of cytotoxic, endocrine, targeted agents and immunotherapy during pregnancy. Part I: Solid tumors
Φόρτωση...
Ημερομηνία
Συγγραφείς
Azim, H. A., Jr.
Peccatori, F. A.
Pavlidis, N.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Cancer Treat Rev
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
The association of cancer and pregnancy is increasingly encountered nowadays in clinical practice. Due to the relative rarity of the situation, it lacks a systematized approach. Different systemic therapies are used in managing cancer with uncertainty regarding the potential hazards they could pose on the pregnancy and/or the fetus. We have performed a systematic review of literature to identify all reports addressing cancer patients who were exposed to any of the known systemic therapies during the course of the pregnancy. The results were discussed in two parts; part I addresses pregnant patients with solid tumors while part I for those with hematological malignancies. In part I, we identified different solid tumors diagnosed and treated during the course of pregnancy. Breast cancer was the most commonly treated followed by ovarian cancer. Other tumors were treated as well including lung cancer, cervical cancer, sarcoma and melanomas. It is important to acknowledge the intent of therapy (palliative vs. curative) and the patients has to be properly counseled to reach an informed decision. We aim to provide a more robust consensus on how to approach these cases and provide a higher degree of evidence to support the safety of applying certain management strategies over the other.
Περιγραφή
Λέξεις-κλειδιά
Antineoplastic Agents/administration & dosage/*therapeutic use, Dose-Response Relationship, Drug, Female, Humans, Immunosuppressive Agents/administration & dosage/*therapeutic use, Immunotherapy/*methods, Neoplasms/*drug therapy, Pregnancy, Pregnancy Complications, Neoplastic/*drug therapy, Pregnancy Outcome, Selective Estrogen Receptor Modulators/administration & dosage/*therapeutic use
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/20015593
http://ac.els-cdn.com/S0305737209001819/1-s2.0-S0305737209001819-main.pdf?_tid=94865571e9d19575840a5da09eac4a8f&acdnat=1333609802_6adbd880a4f05ffb488180f92d0cbad3
http://ac.els-cdn.com/S0305737209001819/1-s2.0-S0305737209001819-main.pdf?_tid=94865571e9d19575840a5da09eac4a8f&acdnat=1333609802_6adbd880a4f05ffb488180f92d0cbad3
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής