The effects of ezetimibe and/or orlistat on triglyceride-rich lipoprotein metabolism in obese hypercholesterolemic patients
| dc.contributor.author | Nakou, E. S. | en |
| dc.contributor.author | Filippatos, T. D. | en |
| dc.contributor.author | Agouridis, A. P. | en |
| dc.contributor.author | Kostara, C. | en |
| dc.contributor.author | Bairaktari, E. T. | en |
| dc.contributor.author | Elisaf, M. S. | en |
| dc.date.accessioned | 2015-11-24T19:41:45Z | |
| dc.date.available | 2015-11-24T19:41:45Z | |
| dc.identifier.issn | 1558-9307 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/24526 | |
| dc.rights | Default Licence | - |
| dc.subject | Anti-Obesity Agents/*pharmacology | en |
| dc.subject | Anticholesteremic Agents/pharmacology | en |
| dc.subject | Apolipoprotein C-II/metabolism | en |
| dc.subject | Apolipoprotein C-III/metabolism | en |
| dc.subject | Azetidines/*pharmacology | en |
| dc.subject | Diet, Fat-Restricted | en |
| dc.subject | Drug Therapy, Combination | en |
| dc.subject | Female | en |
| dc.subject | Humans | en |
| dc.subject | Lactones/*pharmacology | en |
| dc.subject | Male | en |
| dc.subject | Middle Aged | en |
| dc.subject | Obesity/diet therapy/*drug therapy | en |
| dc.subject | Triglycerides/*metabolism | en |
| dc.title | The effects of ezetimibe and/or orlistat on triglyceride-rich lipoprotein metabolism in obese hypercholesterolemic patients | en |
| heal.abstract | We investigated the factors influencing triglycerides (TG) reduction during ezetimibe, alone or combined with orlistat, administration. Eighty-six obese hypercholesterolemic subjects were prescribed a low-fat diet and were randomized to ezetimibe (E group), orlistat (O group), or both (OE group) for 6 months. Plasma TG and apolipoprotein (apo) C-III reduction was significantly greater in the combination group compared with monotherapy. Multivariate analysis showed that in E group apoC-III reduction and baseline TG levels were independently positively correlated, whereas baseline apoC-II levels were negatively correlated, with TG lowering. In OE group apoC-III reduction was the only independent contributor to TG reduction. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1007/s11745-010-3409-0 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/20379853 | - |
| heal.identifier.secondary | http://www.springerlink.com/content/24k51128823674n1/fulltext.pdf | - |
| heal.journalName | Lipids | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2010 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
Αρχεία
Φάκελος/Πακέτο αδειών
1 - 1 of 1
Φόρτωση...
- Ονομα:
- license.txt
- Μέγεθος:
- 1.74 KB
- Μορφότυπο:
- Item-specific license agreed upon to submission
- Περιγραφή: