Synchronous occurrence of neuroendocrine colon carcinoma and hairy cell leukemia

dc.contributor.authorSalemis, N. S.en
dc.contributor.authorPinialidis, D.en
dc.contributor.authorTsiambas, E.en
dc.contributor.authorGakis, C.en
dc.contributor.authorNakos, G.en
dc.contributor.authorSambaziotis, D.en
dc.contributor.authorChristofyllakis, C.en
dc.date.accessioned2015-11-24T19:43:29Z
dc.date.available2015-11-24T19:43:29Z
dc.identifier.issn1941-6636-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/24765
dc.rightsDefault Licence-
dc.subjectAgeden
dc.subjectAntineoplastic Combined Chemotherapy Protocols/therapeutic useen
dc.subjectCarcinoma, Neuroendocrine/drug therapy/*pathologyen
dc.subjectColonic Neoplasms/drug therapy/*pathologyen
dc.subjectColonoscopyen
dc.subjectHumansen
dc.subjectIncidenceen
dc.subjectLeukemia, Hairy Cell/drug therapy/*pathologyen
dc.subjectMaleen
dc.subjectNeoplasm Stagingen
dc.subject*Neoplasms, Multiple Primaryen
dc.subjectRisk Factorsen
dc.subjectTomography, X-Ray Computeden
dc.subjectTreatment Outcomeen
dc.titleSynchronous occurrence of neuroendocrine colon carcinoma and hairy cell leukemiaen
heal.abstractBACKGROUND-PURPOSE: The risk of secondary malignancy development in patients with hairy cell leukemia has been evaluated in several studies with varying results. The aim of this study is to describe a case of synchronous occurrence of neuroendocrine colon carcinoma and hairy cell leukemia. METHODS: A 69-year-old man presented with rectal bleeding. Colonoscopy revealed a rectal tumor, whereas biopsy specimens revealed a poorly differentiated carcinoma. During the preoperative evaluation, pancytopenia was detected. RESULTS: At laparotomy, a mass was detected 16 cm from the anal verge and an anterior resection of the rectum was performed. Detailed histological and immunohistochemical analyses revealed a poorly differentiated neuroendocrine carcinoma of the rectum. Postoperative evaluation of pancytopenia revealed hairy cell leukemia. The patient was initially treated with chemotherapy for hairy cell leukemia followed by chemotherapy for neuroendocrine colon carcinoma. Survival was 44 months. CONCLUSIONS: To our knowledge, synchronous occurrence of neuroendocrine colon carcinoma and hairy cell leukemia has not been previously reported in the literature. Given the rare incidence of both entities in the general population, it is highly unlikely that they occurred together by chance. Further research is needed to determine what would be the optimal management options of patients with simultaneous hairy cell leukemia and a neuroendocrine colon cancer.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1007/s12029-010-9167-7-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/20524083-
heal.identifier.secondaryhttp://www.springerlink.com/content/u304668727x15212/fulltext.pdf-
heal.journalNameJ Gastrointest Canceren
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2011-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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