Multiple actions of high-density lipoprotein
| dc.contributor.author | Florentin, M. | en |
| dc.contributor.author | Liberopoulos, E. N. | en |
| dc.contributor.author | Wierzbicki, A. S. | en |
| dc.contributor.author | Mikhailidis, D. P. | en |
| dc.date.accessioned | 2015-11-24T19:03:08Z | |
| dc.date.available | 2015-11-24T19:03:08Z | |
| dc.identifier.issn | 1531-7080 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/19872 | |
| dc.rights | Default Licence | - |
| dc.subject | Anti-Infective Agents/metabolism | en |
| dc.subject | Anti-Inflammatory Agents/metabolism | en |
| dc.subject | Antioxidants/metabolism | en |
| dc.subject | Atherosclerosis/*metabolism | en |
| dc.subject | Endothelium, Vascular/metabolism | en |
| dc.subject | Fibrinolytic Agents/metabolism | en |
| dc.subject | Humans | en |
| dc.subject | Kidney/metabolism | en |
| dc.subject | Lipoproteins, HDL/chemistry/*metabolism | en |
| dc.subject | Molecular Structure | en |
| dc.title | Multiple actions of high-density lipoprotein | en |
| heal.abstract | PURPOSE OF REVIEW: The most accepted property of high-density lipoprotein is reverse cholesterol transport. However, other beneficial actions may contribute to the antiatherogenic role of high-density lipoprotein. This review addresses the action of high-density lipoprotein beyond reverse cholesterol transport. RECENT FINDINGS: High-density lipoprotein cholesterol levels are inversely associated with coronary heart disease and other forms of vascular disease. Apart from transferring excess cholesterol to the liver, high-density lipoprotein exhibits favorable effects on oxidation, inflammation, thrombosis and endothelial function. Some of these actions are at least in part attributed to high-density lipoprotein-associated enzymes, such as paraoxonase and platelet-activating factor acetylhydrolase. However, high-density lipoprotein can become dysfunctional and proatherogenic under certain circumstances. SUMMARY: Current data suggest that high-density lipoprotein possesses various properties beyond reverse cholesterol transport. However, many issues on the exact role of high-density lipoprotein remain unknown. Future research is needed. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1097/HCO.0b013e3283043806 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/18520722 | - |
| heal.journalName | Curr Opin Cardiol | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2008 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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