Outcome of patients with haemodynamically stable ventricular tachycardia treated with an implantable cardioverter-defibrillator

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dc.contributor.authorKolettis, T. M.en
dc.contributor.authorKrikos, V. D.en
dc.contributor.authorApostolidis, D.en
dc.contributor.authorNaka, K. K.en
dc.contributor.authorKatsouras, C. S.en
dc.contributor.authorSourla, E.en
dc.contributor.authorMichalis, L. K.en
dc.date.accessioned2015-11-24T19:00:32Z
dc.date.available2015-11-24T19:00:32Z
dc.identifier.issn1109-9666-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19550
dc.rightsDefault Licence-
dc.subjectAgeden
dc.subjectAnti-Arrhythmia Agents/therapeutic useen
dc.subject*Defibrillators, Implantableen
dc.subjectDisease-Free Survivalen
dc.subjectElectrophysiologic Techniques, Cardiacen
dc.subjectFemaleen
dc.subjectHemodynamicsen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectPrognosisen
dc.subjectProportional Hazards Modelsen
dc.subjectRecurrenceen
dc.subjectTachycardia, Ventricular/mortality/physiopathology/*therapyen
dc.subjectTreatment Outcomeen
dc.titleOutcome of patients with haemodynamically stable ventricular tachycardia treated with an implantable cardioverter-defibrillatoren
heal.abstractINTRODUCTION: The benefit of implantable cardioverter defibrillator (ICD) therapy in patients with haemodynamically stable ventricular tachycardia (VT) is not well documented. METHODS: In this single-centre observational study, we examined the medical records of 53 patients (48 men, mean age 66 +/- 1 years) treated with an ICD. The patients were classified into four groups with comparable clinical and electrophysiological characteristics, as follows: patients presenting with (a) stable VT, (b) unstable VT, (c) cardiac arrest, and (d) non-sustained VT and induced sustained VT or ventricular fibrillation (VF) on electrophysiological study. Kaplan-Meier event-free survival curves were constructed and the incidence of appropriate device therapy was compared among the four groups. RESULTS: All patients had structural heart disease with a mean ejection fraction of 32.5 +/- 1.3%. During a mean follow-up period of 35.5 +/- 2.7 months, event-free survival was similar in the four groups. However, appropriate device therapy occurred in 9 (81.8%) patients with stable VT, in 6 (44.4%) patients with unstable VT, in 2 (33.3%) patients with cardiac arrest and in 6 (33.3%) patients with non-sustained VT and induced sustained VT/VF. Compared to the total patient cohort, appropriate therapy was significantly (p = 0.024) more common in patients presenting with stable monomorphic VT. In 2 (22.2%) of these patients, the tachycardia rate was faster than the presenting VT. CONCLUSIONS: High recurrence rates are observed in patients with structural heart disease and stable VT, with a considerable proportion being faster than the presenting VT. ICD therapy is beneficial and should be offered in these patients.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18935712-
heal.journalNameHellenic J Cardiolen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2008-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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