Relationship between preimplantation host weight and growth of the mouse adenocarcinoma EO 771

dc.contributor.authorBassukas, I. D.en
dc.contributor.authorMaurer-Schultze, B.en
dc.date.accessioned2015-11-24T18:54:32Z
dc.date.available2015-11-24T18:54:32Z
dc.identifier.issn0258-851X-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18696
dc.rightsDefault Licence-
dc.subjectAdenocarcinoma/*pathologyen
dc.subjectAnimalsen
dc.subject*Body Weighten
dc.subjectLegen
dc.subjectMaleen
dc.subjectMammary Neoplasms, Experimentalen
dc.subjectMiceen
dc.subjectMice, Inbred C57BLen
dc.subjectNeoplasm Transplantationen
dc.titleRelationship between preimplantation host weight and growth of the mouse adenocarcinoma EO 771en
heal.abstractGrowth curves of 26 EO 771 adenocarcinomas transplanted under identical conditions into 26 syngeneic C57bl/6 male mice of the same age but with different body weight were analyzed using the method of the recursion formula of the Gompertz function. The results of this analysis were then related to the body weight of the animals at the time of tumor implantation. Although all tumors grew according to the Gompertz mode of growth, the growth curves differed from each other. Moreover, there is a statistically significant correlation between the parameters of the individual growth curves and the corresponding animal weight at the time of tumor implantation (p less than 0.025). In animals with higher body weight the tumors grew with a higher initial growth rate and subsequently with a faster growth deceleration compared to animals with lower body weight. The physiological basis for this relationship is unknown but the question arises whether this relationship also has some meaning for human malignancies.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/1627749-
heal.journalNameIn Vivoen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1992-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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