Study of the Glycogenolytic Action of Platelet-Activating-Factor in Tetrahymena-Pyriformis

dc.contributor.authorTsangaris, G. T.en
dc.contributor.authorDemopoulos, C. A.en
dc.contributor.authorTsoukatos, D. C.en
dc.contributor.authorKapoulas, V. M.en
dc.date.accessioned2015-11-24T16:48:36Z
dc.date.available2015-11-24T16:48:36Z
dc.identifier.issn0742-8413-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/9346
dc.rightsDefault Licence-
dc.subjectacetylglyceryl ether phosphorylcholineen
dc.subjectperfused-rat-liveren
dc.subjectguanylate-cyclaseen
dc.subjectrabbit plateletsen
dc.subjectstimulationen
dc.subjectmetabolismen
dc.subjectagepcen
dc.subject1-o-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholineen
dc.subjectphosphatidylinositolen
dc.subjectvasoconstrictionen
dc.titleStudy of the Glycogenolytic Action of Platelet-Activating-Factor in Tetrahymena-Pyriformisen
heal.abstract1. A novel action of AGEPC on non-inflammatory cells was revealed, namely the ability to stimulate glycogenolysis in Tetrahymena pyriformis cells. 2. The glycogenolytic effect of AGEPC seems to be dependent on Ca2+ transport and regulation, thus the effects are completely inhibited by Verapamile and partially by EGTA. 3. The influence of Propranolol, Labetalol, Atenolol and Theophylline in the glycogenolytic effect of AGEPC are also studied. 4. Our findings suggest that the AGEPC promoted glycogenolysis in Tetrahymena through a mechanism distinct from that of catecholamines.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondary<Go to ISI>://A1992JQ72000026-
heal.journalNameComparative Biochemistry and Physiology C-Pharmacology Toxicology & Endocrinologyen
heal.journalTypepeer reviewed-
heal.languageen-
heal.publicationDate1992-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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