Influence of a proton pump inhibitor-based therapy on Helicobacter pylori strain selection
| dc.contributor.author | Hazell, S. L. | en |
| dc.contributor.author | Mitchell, H. M. | en |
| dc.contributor.author | Hanna, G. | en |
| dc.contributor.author | Daskalopoulos, G. | en |
| dc.date.accessioned | 2015-11-24T19:10:04Z | |
| dc.date.available | 2015-11-24T19:10:04Z | |
| dc.identifier.issn | 0934-9723 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/20786 | |
| dc.rights | Default Licence | - |
| dc.subject | 2-Pyridinylmethylsulfinylbenzimidazoles | en |
| dc.subject | Anti-Ulcer Agents/pharmacology/*therapeutic use | en |
| dc.subject | Biopsy | en |
| dc.subject | Double-Blind Method | en |
| dc.subject | Gastric Mucosa/microbiology | en |
| dc.subject | Helicobacter Infections/*drug therapy/microbiology | en |
| dc.subject | Helicobacter pylori/classification/*genetics/isolation & purification | en |
| dc.subject | Humans | en |
| dc.subject | Omeprazole/*analogs & derivatives/pharmacology/therapeutic use | en |
| dc.subject | Proton Pumps/*antagonists & inhibitors | en |
| dc.subject | Pyloric Antrum/microbiology | en |
| dc.subject | Random Amplified Polymorphic DNA Technique | en |
| dc.title | Influence of a proton pump inhibitor-based therapy on Helicobacter pylori strain selection | en |
| heal.abstract | The influence of the proton pump inhibitor lansoprazole on strain diversity in Helicobacter pylori infected patients was investigated. Multiple isolates of Helicobacter pylori obtained pre- and post-therapy from gastric antral and body biopsies in 22 patients were compared using the random amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR) for analysis. Post-therapy strains exhibiting novel RAPD-profiles were found in 5 of 22 patients (4 of 11 patients treated with lansoprazole alone and 1 of 11 patients treated with lansoprazole plus amoxicillin). Proton pump inhibition may affect the microecology of the stomach by influencing the colonisation patterns of specific strains. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/9272389 | - |
| heal.identifier.secondary | http://www.springerlink.com/content/u5037q2907786677/fulltext.pdf | - |
| heal.journalName | Eur J Clin Microbiol Infect Dis | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 1997 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
Αρχεία
Φάκελος/Πακέτο αδειών
1 - 1 of 1
Φόρτωση...
- Ονομα:
- license.txt
- Μέγεθος:
- 1.74 KB
- Μορφότυπο:
- Item-specific license agreed upon to submission
- Περιγραφή: