Synthesis and characterization of Pd(II) and Pt(II) complexes with triazolopyrimidine derivatives: The crystal structure of [Pd2L2Cl4] where L=5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidine
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Lekkas, N.
Hadjiliadis, N.
Garoufis, A.
Kobe, J.
Bernhardt, P. V.
Tiekink, E. R. T.
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peer reviewed
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Inorganica Chimica Acta
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The Pd(II) and Pt(II) complexes with triazolopyrimidine C-nucleosides L-1 (5,7-dimethyl-3-(2',3',5'-tri-O-benzoyl-beta-D-ribofuranosyl-s-triazolo)[4,3-a]pyrimidine), L-2 (5,7-dimethyl-3-beta-D-ribofuranosyl-s-triazolo [4,3-a]pyrimidine) and L-3 (5,7-dimethyl[1,5-a]-s-triazolopyrimidine), [Pd(en)(L-1)](NO3)(2), (Pd(bpy)(L-1)](NO3)(2), cis-Pd(L-3)(2)Cl-2, [Pd-2(L-3)(2)Cl-4]center dot H2O, cis-Pd(L-2)(2)Cl-2 and [Pt-3(L-1)(2)Cl-6] were synthesized and characterized by elemental analysis and NMR spectroscopy. The structure of the [Pd-2(L-3)(2)Cl-4]center dot H2O complex was established by Xray crystallography. The two L-3 ligands are found in a head to tail orientation, with a (PdPd)-Pd-... distance of 3.1254(17) angstrom.L-1 coordinates to Pd(II) through N8 and N1 forming polymeric structures. L-2 coordinates to Pd(II) through N8 in acidic solutions (0.1 M HCl) forming complexes of cis-geometry. The Pd(II) coordination to L-2 does not affect the sugar conformation probably due to the high stability of the C-C glycoside bond. (c) 2006 Elsevier B.V. All rights reserved.
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pd(ii) and pt(ii) complexes, c-nucleosides, triazolopyrimidines, x-ray crystal structure, bridgehead c-nucleosides, antitumor-activity, nmr-spectroscopy, amino-acids, platinum(ii), formycin, ligands
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<Go to ISI>://000240862000017
http://ac.els-cdn.com/S0020169306003525/1-s2.0-S0020169306003525-main.pdf?_tid=898a0d2c-5807-11e3-8a0a-00000aacb35e&acdnat=1385627694_42481af7053504df2c34c3603dd0bb75
http://ac.els-cdn.com/S0020169306003525/1-s2.0-S0020169306003525-main.pdf?_tid=898a0d2c-5807-11e3-8a0a-00000aacb35e&acdnat=1385627694_42481af7053504df2c34c3603dd0bb75
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en
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Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας