Percutaneous coronary intervention for late reperfusion after myocardial infarction in stable patients
| dc.contributor.author | Ioannidis, J. P. | en |
| dc.contributor.author | Katritsis, D. G. | en |
| dc.date.accessioned | 2015-11-24T18:59:45Z | |
| dc.date.available | 2015-11-24T18:59:45Z | |
| dc.identifier.issn | 1097-6744 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/19404 | |
| dc.rights | Default Licence | - |
| dc.subject | *Angioplasty, Balloon, Coronary | en |
| dc.subject | Female | en |
| dc.subject | Heart Failure/etiology | en |
| dc.subject | Humans | en |
| dc.subject | Male | en |
| dc.subject | Myocardial Infarction/*drug therapy/mortality/*therapy | en |
| dc.subject | Myocardial Reperfusion/methods | en |
| dc.subject | Stroke Volume | en |
| dc.title | Percutaneous coronary intervention for late reperfusion after myocardial infarction in stable patients | en |
| heal.abstract | BACKGROUND: Results of randomized trials that have compared mechanical coronary artery recanalization versus medical therapy for total occlusion late after myocardial infarction (MI) have been conflicting. METHODS: We performed a meta-analysis of randomized trials comparing percutaneous coronary intervention (PCI) with medical therapy in stable patients with an occluded artery 1 to 45 days after MI. Six trials and one substudy were included with data on 2617 patients for the clinical outcomes and 653 patients for determination of ejection fraction (EF) during follow-up. Outcomes included death, MI, death or MI, congestive heart failure (CHF), and change in left ventricular EF. RESULTS: There were no statistically significant differences for any clinical outcome, with trends for an increase in MI (risk ratio 1.26, P = .19) and decrease in CHF (risk ratio 0.67, P = .19) in the PCI arm. The PCI arm showed a slight superiority in left ventricular EF (2%, 95% CI 0.1%-2.8%). Early smaller studies showed formally statistically significant benefits for CHF and EF, but the much larger Occluded Artery Trial and Total Occlusion Study of Canada 2 found no benefit. For CHF, the difference between early smaller studies and Occluded Artery Trial was beyond chance (P = .02). CONCLUSIONS: Percutaneous coronary intervention does not seem to confer any benefits when used for late revascularization of occluded arteries after MI in stable patients. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1016/j.ahj.2007.07.049 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/18035076 | - |
| heal.identifier.secondary | http://ac.els-cdn.com/S0002870307006680/1-s2.0-S0002870307006680-main.pdf?_tid=cb2515330361e735d76d752fca0e6d34&acdnat=1333363861_f4add5b22fcfb4d1c718f4edccd0b94e | - |
| heal.journalName | Am Heart J | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2007 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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