Palladium(II) complexes of 2-acetylpyridine N(4)-propyl, N(4)-dipropyl- and 3-hexamethyleneiminylthiosemicarbazones with potentially interesting biological activity. Synthesis, spectral properties, antifungal and in vitro antitumor activity

dc.contributor.authorKovalaDemertzi, D.en
dc.contributor.authorDomopoulou, A.en
dc.contributor.authorDemertzis, M. A.en
dc.contributor.authorPapageorgiou, A.en
dc.contributor.authorWest, D. X.en
dc.date.accessioned2015-11-24T16:43:57Z
dc.date.available2015-11-24T16:43:57Z
dc.identifier.issn0277-5387-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/8756
dc.rightsDefault Licence-
dc.subjectnew palladium complexesen
dc.subject2-acetylpyridine thiosemicarbazonesen
dc.subjectantitumor activityen
dc.subjectmetal ion complexesen
dc.subjectcopper(ii) complexesen
dc.subjectredox behavioren
dc.subjectthiosemicarbazonesen
dc.subjectn-4-dipropylthiosemicarbazonesen
dc.subjectn-4-diethylthiosemicarbazonesen
dc.subjectelectrochemistryen
dc.titlePalladium(II) complexes of 2-acetylpyridine N(4)-propyl, N(4)-dipropyl- and 3-hexamethyleneiminylthiosemicarbazones with potentially interesting biological activity. Synthesis, spectral properties, antifungal and in vitro antitumor activityen
heal.abstractSome new palladium(II) complexes of 2-acetylpyridine N(4)-propyl-and N(4)dipropyl- and 3-hexamethyleneiminylthiosemicarbazones with potentially interesting biological activity were described. The thiosemicarbazones and their palladium(II) complexes have been characterized by spectroscopic, and electrochemical techniques. The protonation constants of HAc4P K-a1 and K-a2, were determined by spectrophotometry and the pK(1a) and pK(a2) values are equal to 12.23 +/- 0.02 and 4.11 +/- 0.02. The antifungal properties and the effect selected compounds on DNA synthesis of P388 and L1210 cell cultures is reported. (C) 1997 Elsevier Science Ltd.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondary<Go to ISI>://A1997XQ92400022-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0277538797001071/1-s2.0-S0277538797001071-main.pdf?_tid=6a0549a33fd66837f4813a618bc57f30&acdnat=1333028721_c25fac89265570f2afe50784f3f8401f-
heal.journalNamePolyhedronen
heal.journalTypepeer reviewed-
heal.languageen-
heal.publicationDate1997-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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