Heterotopic ossification after total hip arthroplasty (THA) in congenital hip disease: comparison of two different prophylactic protocols
Φόρτωση...
Ημερομηνία
Συγγραφείς
Pakos, E. E.
Stafilas, K. S.
Politis, A. N.
Tsekeris, P. G.
Mitsionis, G.
Xenakis, T. A.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Clinical & Translational Oncology
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
We aimed to evaluate retrospectively the efficacy of combined postoperative radiotherapy and indomethacin compared to indomethacin alone for the prevention of heterotopic ossification (HO) in high-risk patients with congenital disease of hip (CDH) undergoing total hip arthroplasty (THA). Fifty-five patients received indomethacin alone (Group A), while 44 patients received the combined protocol (Group B). Patients a parts per thousand yen55 years were enrolled in Group B and those younger than 55 years in Gro up A. Patients were evaluated radiologically for the pre sence of HO 6 months after the operation. The incidence of HO in Group A was 34.5% (95% confidence interval 22.2-48.6%), while the respective incidence in Group B patients was 27.3% (95% CI 15.0-42.8%). The difference was not statistically significant (p=0.5). No significant treatment-related side effects were reported. This is the first study evaluating the impact of HO prophylaxis in an immiscible population of patients with secondary arthritis due to CDH undergoing THA. Further future randomised evidence is required in order to ascertain the observed trend towards improved efficacy of the combined protocol for HO development.
Περιγραφή
Λέξεις-κλειδιά
congenital hip disease, total hip arthroplasty, heterotopic ossification, radiotherapy, indomethacin, high-risk patients, bone-formation, ectopic ossification, predisposing factors, radiation-therapy, prevention, indomethacin, radiotherapy, replacement, irradiation
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
<Go to ISI>://000263511800009
http://link.springer.com/content/pdf/10.1007%2Fs12094-009-0322-1.pdf
http://link.springer.com/content/pdf/10.1007%2Fs12094-009-0322-1.pdf
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών και Τεχνολογιών. Τμήμα Βιολογικών Εφαρμογών και Τεχνολογιών