Giardia lamblia intestinalis: a new pathogen with possible link to Kikuchi-Fujimoto disease. An additional element in the disease jigsaw

dc.contributor.authorCharalabopoulos, K.en
dc.contributor.authorCharalabopoulos, A.en
dc.contributor.authorPapadopoulou, C. H.en
dc.contributor.authorPapalimneou, V.en
dc.date.accessioned2015-11-24T19:14:44Z
dc.date.available2015-11-24T19:14:44Z
dc.identifier.issn1368-5031-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/21378
dc.rightsDefault Licence-
dc.subjectAdolescenten
dc.subjectAnimalsen
dc.subjectAntiprotozoal Agents/*therapeutic useen
dc.subjectC-Reactive Protein/analysisen
dc.subjectFemaleen
dc.subjectGiardia lambliaen
dc.subjectGiardiasis/*complicationsen
dc.subjectHistiocytic Necrotizing Lymphadenitis/drug therapy/*parasitology/pathologyen
dc.subjectHumansen
dc.subjectImmunohistochemistryen
dc.subjectLymph Nodes/pathologyen
dc.subjectMetronidazole/*therapeutic useen
dc.titleGiardia lamblia intestinalis: a new pathogen with possible link to Kikuchi-Fujimoto disease. An additional element in the disease jigsawen
heal.abstractA 16-year-old Caucasian girl of Albanian origin was admitted to the hospital complaining of intermittent fever (38 degrees C) for a week, nausea, vomiting, and abnormal laboratory findings (elevated serum aminotransferases levels AST/ALT 77/40 U/l and erythrocyte sedimentation rate 80 mm/first hour, as well as leukopenia 2.5 x 10(3)/mm3), which were found in a blood examination. Physical examination revealed slight hepatomegaly and splenomegaly, as well as cervical and axillary lymphadenopathy. A diagnostic open lymph node biopsy was performed and Kikuchi-Fujimoto disease (KFD) was established based on the characteristic histological pattern. Other abnormal laboratory findings were C-reactive protein 6.8 mg/dl and serum lactate dehydrogenase 900 U/l. Her history included a diarrhoea syndrome 2 months before the present admission, during the summer holidays, for which she was treated with metronidazole. At that time, characteristic cysts of giardia lamblia intestinalis were observed in the stools. Herein, we present this case hypothesising that the protozoal infection caused by the giardia lamblia intestinalis was probably triggering an immune response leading to KFD. The patient's age in combination with this firstly reported protozoal pathogen, as a triggering agent leading to KFD, consist a very interesting originality. Additionally, some review data is also given.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/15646421-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1111/j.1742-1241.2004.00130.x/asset/j.1742-1241.2004.00130.x.pdf?v=1&t=h0c0vzui&s=97c9b2b13eea77eca36c087edb31b6702366c031-
heal.journalNameInt J Clin Practen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2004-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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