Vaccination in adult patients with auto-immune inflammatory rheumatic diseases: a systematic literature review for the European League Against Rheumatism evidence-based recommendations for vaccination in adult patients with auto-immune inflammatory rheumatic diseases
Φόρτωση...
Ημερομηνία
Συγγραφείς
van Assen, S.
Elkayam, O.
Agmon-Levin, N.
Cervera, R.
Doran, M. F.
Dougados, M.
Emery, P.
Geborek, P.
Ioannidis, J. P.
Jayne, D. R.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Autoimmun Rev
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
OBJECTIVES: To present the systematic literature review (SLR), which formed the basis for the European League Against Rheumatism (EULAR) evidence-based recommendations for vaccination in adult patients with auto-immune inflammatory rheumatic diseases (AIIRD). METHODS: AIIRD, vaccines and immunomodulating drugs, as well as eight key questions were defined by the multidisciplinary expert committee commissioned by EULAR for developing the recommendations. A SLR was performed using MedLine through October 2009 and including data from meta-analyses, systematic reviews, randomized trials, and observational studies, excluding case series with </= 5 participants. Articles in English and regarding patients >/= 16 years of age, were eligible. RESULTS: Several vaccine-preventable infections (VPI) occur more often in AIIRD-patients and most vaccines are efficacious in AIIRD-patients, even when treated with immunomodulating agents, except rituximab. There does not appear to be an increase in vaccination-related harms in vaccinated patients with AIIRD in comparison with unvaccinated patients with AIIRD. However, these studies are underpowered and therefore not conclusive. CONCLUSION: Based on the current evidence from the literature, recommendations for vaccination in patients with AIIRD were made. However, more research is needed in particular regarding incidence of VPI, harms of vaccination and the influence of (new and established) immunomodulating agents on vaccination efficacy.
Περιγραφή
Λέξεις-κλειδιά
Adult, Antirheumatic Agents/therapeutic use, Autoimmune Diseases/*complications/drug therapy, Disease Susceptibility/chemically induced/complications, *Evidence-Based Medicine, Humans, Immunization, Secondary/statistics & numerical data, Immunologic Factors/therapeutic use, Opportunistic Infections/*complications/*prevention & control, Rheumatic Diseases/*complications/drug therapy, *Vaccination/economics/statistics & numerical data, Vaccines/administration & dosage/adverse effects/standards
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/21182987
http://ac.els-cdn.com/S1568997210002636/1-s2.0-S1568997210002636-main.pdf?_tid=ce7c6c9fe78172babda2886adcabc9bf&acdnat=1333363442_b2400cd2c8ab6957ae9cfd4a568311c9
http://ac.els-cdn.com/S1568997210002636/1-s2.0-S1568997210002636-main.pdf?_tid=ce7c6c9fe78172babda2886adcabc9bf&acdnat=1333363442_b2400cd2c8ab6957ae9cfd4a568311c9
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής