Correlative histologic and serologic findings of sicca syndrome in patients with systemic lupus erythematosus

dc.contributor.authorMoutsopoulos, H. M.en
dc.contributor.authorKlippel, J. H.en
dc.contributor.authorPavlidis, N.en
dc.contributor.authorWolf, R. O.en
dc.contributor.authorSweet, J. B.en
dc.contributor.authorSteinberg, A. D.en
dc.contributor.authorChu, F. C.en
dc.contributor.authorTarpley, T. M.en
dc.date.accessioned2015-11-24T19:26:40Z
dc.date.available2015-11-24T19:26:40Z
dc.identifier.issn0004-3591-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22750
dc.rightsDefault Licence-
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAutoantibodies/*analysisen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectLupus Erythematosus, Systemic/*complications/immunology/pathologyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectProspective Studiesen
dc.subjectSalivary Glands/*pathologyen
dc.subjectSalivary Glands, Minor/*pathologyen
dc.subjectSjogren's Syndrome/*complications/immunology/pathologyen
dc.titleCorrelative histologic and serologic findings of sicca syndrome in patients with systemic lupus erythematosusen
heal.abstractWe prospectively evaluated 24 patients with systemic lupus erythematosus for clinical, histologic, and serologic evidence of sicca syndrome. Abnormalties suggestive of sicca syndrome in patients with systemic lupus were identified by parotid scan (58%), questionnaire (54%), labial biopsy (50%), Schirmer's test (21%), and parotid flow rate (13%). An increased frequency of autoantibodies to gamma globulin and cellular antigen SS-A was detected in lupus patients with histologic changes on labial biopsy. The serologic findings are similar to those of patients with sicca syndrome alone with the exception of the reduced incidence of anti-SS-B in patients with systemic lupus.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/7352942-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1002/art.1780230107/asset/1780230107_ftp.pdf?v=1&t=h0nibg54&s=f307fe867ecde2f8c30af212e7525ea4b1db14b1-
heal.journalNameArthritis Rheumen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1980-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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