Treatment of refractory unstable angina in geographically isolated areas without cardiac surgery. Invasive versus conservative strategy (TRUCS study)
| dc.contributor.author | Michalis, L. K. | en |
| dc.contributor.author | Stroumbis, C. S. | en |
| dc.contributor.author | Pappas, K. | en |
| dc.contributor.author | Sourla, E. | en |
| dc.contributor.author | Niokou, D. | en |
| dc.contributor.author | Goudevenos, J. A. | en |
| dc.contributor.author | Siogas, C. | en |
| dc.contributor.author | Sideris, D. A. | en |
| dc.date.accessioned | 2015-11-24T19:05:24Z | |
| dc.date.available | 2015-11-24T19:05:24Z | |
| dc.identifier.issn | 0195-668X | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/20188 | |
| dc.rights | Default Licence | - |
| dc.subject | *Air Ambulances | en |
| dc.subject | Angina, Unstable/*drug therapy/*surgery | en |
| dc.subject | Angioplasty | en |
| dc.subject | Coronary Artery Bypass | en |
| dc.subject | Female | en |
| dc.subject | Greece | en |
| dc.subject | Humans | en |
| dc.subject | Male | en |
| dc.subject | *Medically Underserved Area | en |
| dc.subject | Middle Aged | en |
| dc.subject | *Myocardial Reperfusion | en |
| dc.subject | Platelet Aggregation Inhibitors/*therapeutic use | en |
| dc.subject | Prospective Studies | en |
| dc.subject | Treatment Outcome | en |
| dc.title | Treatment of refractory unstable angina in geographically isolated areas without cardiac surgery. Invasive versus conservative strategy (TRUCS study) | en |
| heal.abstract | AIMS: We compared invasive (on-site coronary angioplasty or emergency air-ambulance transfer for bypass grafting surgery) vs conservative (persistent medical treatment) strategies in the management of refractory unstable angina in geographically isolated hospitals without cardiac surgical facilities. METHODS AND RESULTS: One hundred and forty eight randomized patients with refractory unstable angina were compared on an intention-to-treat basis. Outcomes (invasive vs conservative): (a) in hospital: stabilization (96% vs 43%, P=0.0001), non-fatal myocardial infarction (2.6% vs 4.2%, P=ns), death (1.3% vs 8.3%, P=0.046), combined outcome (3.9% vs 12.5%, P=0.053) and hospitalization (11.4+/-6.3 vs 12.4+/-8.0 days, P=ns). (b) 30-days follow-up: non-fatal myocardial infarction (2.6% vs 4.2%, P=ns), death (2.6% vs 11.1%, P=0.030) and combined outcome (5.3% vs 15.3%, P=0.031). (c) 12 month follow-up: non-fatal myocardial infarction (3. 9% vs 4.2%, P=ns), death (3.9% vs 12.5%, P=0.053), combined outcome (7.9% vs 16.7%, P=ns), re-admissions for unstable angina: (17.1% vs 23.6%, P=ns), late coronary angioplasty: (15.8% vs 11.1%, P=ns) and (d) late coronary bypass grafting: (7.9% vs 12.5%, P=ns). CONCLUSION: Invasive treatment of patients with refractory angina in remote areas without surgical back-up results in significant in-hospital stabilization and a reduction in major events in-hospital and at 30 days. Coronary angioplasty in stand-alone units and air-transfer of these patients seems safe. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1053/euhj.2000.2397 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/11071801 | - |
| heal.identifier.secondary | http://eurheartj.oxfordjournals.org/content/21/23/1954.full.pdf | - |
| heal.journalName | Eur Heart J | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2000 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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