Changes in the Cd Spectra of Calf Thymus DNA Induced by Sequential Polypeptides in Aqueous-Solutions .1.

dc.contributor.authorTsikaris, V.en
dc.contributor.authorPanoupomonis, E.en
dc.contributor.authorSakarellos, C.en
dc.contributor.authorSakarellos-Daitsiotis, M.en
dc.contributor.authorMarraud, M.en
dc.date.accessioned2015-11-24T16:53:34Z
dc.date.available2015-11-24T16:53:34Z
dc.identifier.issn0141-8130-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/10037
dc.rightsDefault Licence-
dc.subjectsequential polypeptidesen
dc.subjectcalf thymus DNAen
dc.subjectcd spectroscopyen
dc.subjectcircular-dichroismen
dc.subjecthistone modelsen
dc.subjectbasic polypeptidesen
dc.subjectnucleic-acidsen
dc.subjectdeoxyribonucleic aciden
dc.subjectthermal-denaturationen
dc.subjectchromatin modelsen
dc.subjectconformationen
dc.subjectarginineen
dc.subjectcomplexesen
dc.titleChanges in the Cd Spectra of Calf Thymus DNA Induced by Sequential Polypeptides in Aqueous-Solutions .1.en
heal.abstractInteractions of calf thymus DNA with sequential polypeptides were studied using c.d. spectroscopy in aqueous solutions. It was found that DNA structural alterations induced by sequential polypeptides (L-Arg-X-Gly)n (where X = L-Val, Leu, Ile, Nva, Nle) are modulated by the nature of the X residue. Thus, the polypeptide (L-Arg-L-Nva-Gly)n induced the 10.2B-DNA form, whereas the polypeptides (L-Arg-L-Ile-Gly)n having one methyl group less on the X residue side chain, did not provide any significant modification to the structure of DNA. The effect of ionic strength from 0.14 M NaCl (physiological value) to zero was also analysed on the basis of the observed c.d. changes and the degree of complexation in the DNA-polypeptides was estimated.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondary<Go to ISI>://A1991GW72800006-
heal.identifier.secondaryhttp://ac.els-cdn.com/014181309190017O/1-s2.0-014181309190017O-main.pdf?_tid=4b7e4e49313ac95459caad245ccdd357&acdnat=1333038921_e11426dbe2612348dd4510e4ccbf9987-
heal.journalNameInt J Biol Macromolen
heal.journalTypepeer reviewed-
heal.languageen-
heal.publicationDate1991-
heal.publisherElsevieren
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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