Effect of rosuvastatin treatment on plasma visfatin levels in patients with primary hyperlipidemia

dc.contributor.authorKostapanos, M. S.en
dc.contributor.authorDerdemezis, C. S.en
dc.contributor.authorFilippatos, T. D.en
dc.contributor.authorMilionis, H. J.en
dc.contributor.authorKiortsis, D. N.en
dc.contributor.authorTselepis, A. D.en
dc.contributor.authorElisaf, M. S.en
dc.date.accessioned2015-11-24T16:57:07Z
dc.date.available2015-11-24T16:57:07Z
dc.identifier.issn0014-2999-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/10539
dc.rightsDefault Licence-
dc.subjectadipokineen
dc.subjecthyperlipidemiaen
dc.subjectrosuvastatinen
dc.subjectvisfatinen
dc.subjectcolony-enhancing factoren
dc.subjecttype-2 diabetes-mellitusen
dc.subjectatorvastatinen
dc.subjectproteinen
dc.titleEffect of rosuvastatin treatment on plasma visfatin levels in patients with primary hyperlipidemiaen
heal.abstractVisfatin is a novel adipokine involved in the process of atherosclerosis. We assessed the effect of rosuvastatin on plasma visfatin levels in patients with primary hyperlipidemia. Eighty hyperlipidemic patients without evidence of cardiovascular disease were randomized to receive either rosuvastatin 10 mg/day or therapeutic lifestyle changes intervention. Plasma visfatin levels were determined at baseline and after 12-weeks post-randomization. Rosuvastatin induced a significant decrease in plasma visfatin levels (17.1 +/- 2.1 versus 15.5 +/- 2.0 ng/ml, P = 0.03). This effect correlated with baseline visfatin levels (r=0.51, P<0.01) and was independent of any lipid-lowering actions of rosuvastatin. (C) 2007 Elsevier B.V. All rights reserved.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primaryDOI 10.1016/j.ejphar.2007.09.019-
heal.identifier.secondary<Go to ISI>://000252870600020-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0014299907010461/1-s2.0-S0014299907010461-main.pdf?_tid=152939bcf612750452cd35fc1ce2ae3c&acdnat=1333111400_4fd422d14f9466d610b7258ecfa4ecd2-
heal.journalNameEuropean Journal of Pharmacologyen
heal.journalTypepeer reviewed-
heal.languageen-
heal.publicationDate2008-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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