Elevated serum uric acid levels in metabolic syndrome: an active component or an innocent bystander?

dc.contributor.authorTsouli, S. G.en
dc.contributor.authorLiberopoulos, E. N.en
dc.contributor.authorMikhailidis, D. P.en
dc.contributor.authorAthyros, V. G.en
dc.contributor.authorElisaf, M. S.en
dc.date.accessioned2015-11-24T19:19:58Z
dc.date.available2015-11-24T19:19:58Z
dc.identifier.issn0026-0495-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22000
dc.rightsDefault Licence-
dc.subjectAnimalsen
dc.subjectHumansen
dc.subjectHyperuricemia/*blood/physiopathologyen
dc.subjectMetabolic Syndrome X/*blood/physiopathologyen
dc.subjectUric Acid/*blooden
dc.titleElevated serum uric acid levels in metabolic syndrome: an active component or an innocent bystander?en
heal.abstractElevated serum uric acid (SUA) levels are commonly seen in patients with the metabolic syndrome (MetS). Several mechanisms, both direct and indirect, connect the increased SUA levels with the established diagnostic criteria of MetS. It is possible that the increased cardiovascular disease risk associated with the MetS is partially attributed to elevated circulating SUA concentration. Several drugs used in the treatment of MetS may alter SUA levels. Thus, lifestyle measures together with the judicious selection of drugs for the treatment of hypertension, dyslipidemia, and insulin resistance associated with MetS may result in a reduction of SUA levels and possibly cardiovascular disease risk. This review summarizes the pathophysiologic association between SUA and MetS and focuses on the prevention of hyperuricemia and its cardiovascular consequences.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1016/j.metabol.2006.05.013-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/16979398-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0026049506001806/1-s2.0-S0026049506001806-main.pdf?_tid=e7dcbd8da3c22538fd1da5a163f28904&acdnat=1333539038_2154ea81a601c7456586b60763929f3d-
heal.journalNameMetabolismen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2006-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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