Prothymosin alpha mRNA levels vary with c-myc expression during tissue proliferation, viral infection and heat shock
| dc.contributor.author | Vareli, K. | en |
| dc.contributor.author | Frangou-Lazaridis, M. | en |
| dc.contributor.author | Tsolas, O. | en |
| dc.date.accessioned | 2015-11-24T18:55:49Z | |
| dc.date.available | 2015-11-24T18:55:49Z | |
| dc.identifier.issn | 0014-5793 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/18936 | |
| dc.rights | Default Licence | - |
| dc.subject | Adenoviridae | en |
| dc.subject | Adenovirus E1A Proteins/genetics | en |
| dc.subject | Animals | en |
| dc.subject | Cell Division | en |
| dc.subject | Cell Line | en |
| dc.subject | *Gene Expression Regulation | en |
| dc.subject | HeLa Cells | en |
| dc.subject | Hot Temperature | en |
| dc.subject | Humans | en |
| dc.subject | Placenta/metabolism | en |
| dc.subject | Protein Precursors/*genetics/metabolism | en |
| dc.subject | Proto-Oncogene Proteins c-myc/*biosynthesis/genetics | en |
| dc.subject | RNA, Messenger/metabolism | en |
| dc.subject | Thymosin/*analogs & derivatives/genetics/metabolism | en |
| dc.title | Prothymosin alpha mRNA levels vary with c-myc expression during tissue proliferation, viral infection and heat shock | en |
| heal.abstract | Expression of prothymosin alpha, an acidic nuclear protein implicated in cellular proliferation, has been reported to be regulated by c-myc in vitro. We have studied the correlation of expression levels between prothymosin alpha and c-myc, using three different in vivo systems, viz. normal ontogenic process of placental development, lytic viral infection and heat shock treatment. The two genes have been found to share a similar expression pattern, although prothymosin alpha mRNA remains always detectable, indicating the existence of yet another mechanism, in addition to c-myc, which regulates its expression in vivo. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/7556624 | - |
| heal.identifier.secondary | http://ac.els-cdn.com/0014579395009386/1-s2.0-0014579395009386-main.pdf?_tid=ecaf472ab8fe500de82a667ca97ea7a8&acdnat=1337849243_877c3bd10930a2e9a5802dcf1976b980 | - |
| heal.journalName | FEBS Lett | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 1995 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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