Epstein-Barr virus in T and natural killer (NK) cell non-Hodgkin's lymphomas
| dc.contributor.author | Kanavaros, P. | en |
| dc.contributor.author | Briere, J. | en |
| dc.contributor.author | Emile, J. F. | en |
| dc.contributor.author | Gaulard, P. | en |
| dc.date.accessioned | 2015-11-24T19:18:43Z | |
| dc.date.available | 2015-11-24T19:18:43Z | |
| dc.identifier.issn | 0887-6924 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/21891 | |
| dc.rights | Default Licence | - |
| dc.subject | Herpesviridae Infections/complications | en |
| dc.subject | Herpesvirus 4, Human/*isolation & purification | en |
| dc.subject | Humans | en |
| dc.subject | Killer Cells, Natural/*virology | en |
| dc.subject | Lymphoma, T-Cell/pathology/*virology | en |
| dc.subject | Nose Neoplasms/pathology/*virology | en |
| dc.subject | Paranasal Sinus Neoplasms/pathology/*virology | en |
| dc.subject | Tumor Markers, Biological/analysis | en |
| dc.subject | Tumor Virus Infections/complications | en |
| dc.title | Epstein-Barr virus in T and natural killer (NK) cell non-Hodgkin's lymphomas | en |
| heal.abstract | Several studies using sensitive in situ hybridization techniques show that, in non-immunocompromised patients, Epstein-Barr virus (EBV) is more frequently detected in lymphomas expressing T cell markers than in B cell lymphomas. Among lymphomas expressing T cell markers, the presence of EBV is highly related to the site of origin of the tumor, being found in nearly all sinonasal lymphomas, in only a proportion of Waldeyer's ring, lung, gastrointestinal and nodal lymphomas, and undetectable in most primary cutaneous lymphomas. The role of EBV in their pathogenesis can be suggested in at least a proportion of extranodal lymphomas (nasal, lung, Waldeyer's ring, gastrointestinal) with T cell markers in which EBV genome is found in most if not all tumor cells (EBV-associated lymphomas) and the transforming LMP-1 protein is frequently expressed. Among these, sinonasal lymphomas constitute a distinct clinicopathologic entity which may present as lethal midline granuloma, are strongly associated with EBV and can be regarded in most cases as true NK cell lymphomas. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/8649060 | - |
| heal.journalName | Leukemia | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 1996 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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