Long-term prognosis of asymptomatic individuals with spontaneous or drug-induced type 1 electrocardiographic phenotype of Brugada syndrome
dc.contributor.author | Letsas, K. P. | en |
dc.contributor.author | Weber, R. | en |
dc.contributor.author | Efremidis, M. | en |
dc.contributor.author | Korantzopoulos, P. | en |
dc.contributor.author | Astheimer, K. | en |
dc.contributor.author | Charalampous, C. | en |
dc.contributor.author | Tsikrikas, S. | en |
dc.contributor.author | Fragakis, N. | en |
dc.contributor.author | Kalusche, D. | en |
dc.contributor.author | Sideris, A. | en |
dc.contributor.author | Arentz, T. | en |
dc.date.accessioned | 2015-11-24T19:06:18Z | |
dc.date.available | 2015-11-24T19:06:18Z | |
dc.identifier.issn | 1532-8430 | - |
dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/20328 | |
dc.rights | Default Licence | - |
dc.subject | Adult | en |
dc.subject | Brugada Syndrome/*chemically induced/*physiopathology/therapy | en |
dc.subject | Defibrillators, Implantable | en |
dc.subject | Electrocardiography/*methods | en |
dc.subject | Female | en |
dc.subject | Follow-Up Studies | en |
dc.subject | Humans | en |
dc.subject | Male | en |
dc.subject | Phenotype | en |
dc.subject | Prognosis | en |
dc.subject | Retrospective Studies | en |
dc.subject | Risk Assessment | en |
dc.title | Long-term prognosis of asymptomatic individuals with spontaneous or drug-induced type 1 electrocardiographic phenotype of Brugada syndrome | en |
heal.abstract | BACKGROUND: Risk stratification of asymptomatic individuals with type 1 electrocardiogram (ECG) phenotype of Brugada syndrome (BS) still remains controversial. This study investigated the long-term prognosis of asymptomatic subjects with spontaneous or drug-induced type 1 ECG pattern of BS. METHODS AND RESULTS: Data from 33 apparently healthy individuals (30 males; age, 43.6 +/- 13.4 years) with spontaneous (n = 12) or drug-induced (n = 21) type 1 ECG pattern of BS were retrospectively analyzed. Thirteen subjects (39.4%) displayed a positive family history of BS and/or sudden cardiac death. Electrophysiologic study was performed in 16 subjects, and programed right ventricular stimulation induced polymorphic ventricular tachycardia in 9 (56.3%) of them. A cardioverter defibrillator was implanted in 6 cases. During a mean follow-up period of 5.3 +/- 2.8 years, all subjects remained asymptomatic. None of them had syncope or cardioverter defibrillator discharges due to ventricular arrhythmias. CONCLUSIONS: Asymptomatic individuals with spontaneous or drug-induced type 1 ECG phenotype of BS display a benign clinical course during long-term follow-up. | en |
heal.access | campus | - |
heal.fullTextAvailability | TRUE | - |
heal.identifier.primary | 10.1016/j.jelectrocard.2010.12.007 | - |
heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/21419423 | - |
heal.identifier.secondary | http://ac.els-cdn.com/S002207361000628X/1-s2.0-S002207361000628X-main.pdf?_tid=d17c0a67e1086c185e6884c708372788&acdnat=1333964013_2b2a630664a25f0d2261eb928ea88274 | - |
heal.journalName | J Electrocardiol | en |
heal.journalType | peer-reviewed | - |
heal.language | en | - |
heal.publicationDate | 2011 | - |
heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
heal.type | journalArticle | - |
heal.type.el | Άρθρο Περιοδικού | el |
heal.type.en | Journal article | en |
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