Acid-base and electrolyte abnormalities in febrile patients with bacteraemia
| dc.contributor.author | Elisaf, M. S. | en |
| dc.contributor.author | Theodorou, J. | en |
| dc.contributor.author | Pappas, H. | en |
| dc.contributor.author | Siamopoulos, K. C. | en |
| dc.date.accessioned | 2015-11-24T19:38:21Z | |
| dc.date.available | 2015-11-24T19:38:21Z | |
| dc.identifier.issn | 1165-0478 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/24140 | |
| dc.rights | Default Licence | - |
| dc.subject | Acid-Base Imbalance/*etiology | en |
| dc.subject | Acidosis/etiology | en |
| dc.subject | Adult | en |
| dc.subject | Alkalosis/etiology | en |
| dc.subject | Bacteremia/*complications | en |
| dc.subject | Fever/*etiology | en |
| dc.subject | Gram-Negative Bacterial Infections/complications | en |
| dc.subject | Humans | en |
| dc.subject | Hypocalcemia/etiology | en |
| dc.subject | Hypokalemia/etiology | en |
| dc.subject | Hypophosphatemia/etiology | en |
| dc.subject | Magnesium/blood | en |
| dc.subject | Middle Aged | en |
| dc.subject | Water-Electrolyte Imbalance/*etiology | en |
| dc.title | Acid-base and electrolyte abnormalities in febrile patients with bacteraemia | en |
| heal.abstract | OBJECTIVES: Very commonly febrile patients with bacteraemia develop a variety of acid-base and electrolyte disturbances which play a significant role in the morbidity and mortality of these patients. This study was undertaken to describe the pathogenetic mechanisms of these abnormalities in febrile patients with bacteraemia. METHODS: Fifteen febrile patients with bacteraemia, aged 24-62 years, were studied. In all patients blood cultures revealed Gram-negative rods. None of them had septic shock, diabetes mellitus, renal or liver failure and none was receiving drugs influencing acid-base balance and electrolyte levels or was a heavy alcohol consumer. RESULTS: Nine patients had respiratory alkalosis, which was possibly due to bacterial toxins, while the remaining 6 had a wide-gap metabolic (lactic) acidosis coexisting with respiratory alkalosis. Hypokalaemia was found in four patients and was mainly due to respiratory alkalosis. However, kaliuria due to hypomagnesaemia contributed to hypokalaemia in 2 patients. Hypomagnesaemia was detected in 3 patients and was attributed to respiratory alkalosis as well as to magnesiuria induced by metabolic acidosis or phosphate depletion. Hypophosphataemia was found in 5 patients who also had respiratory alkalosis and/or phosphaturia due to metabolic acidosis or hypomagnesaemia. Finally, one patient had multifactorial origin hypocalcaemia. CONCLUSION: Febrile patients with bacteraemia develop a number of acid-base and electrolyte disturbances attributed to various pathogenetic mechanisms. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/8258028 | - |
| heal.journalName | Eur J Med | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 1993 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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