Prevalence of primary Sjogren's syndrome in an elderly population
| dc.contributor.author | Drosos, A. A. | en |
| dc.contributor.author | Andonopoulos, A. P. | en |
| dc.contributor.author | Costopoulos, J. S. | en |
| dc.contributor.author | Papadimitriou, C. S. | en |
| dc.contributor.author | Moutsopoulos, H. M. | en |
| dc.date.accessioned | 2015-11-24T18:56:49Z | |
| dc.date.available | 2015-11-24T18:56:49Z | |
| dc.identifier.issn | 0263-7103 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/19096 | |
| dc.rights | Default Licence | - |
| dc.subject | Aged | en |
| dc.subject | Aged, 80 and over | en |
| dc.subject | Autoantigens/analysis | en |
| dc.subject | Female | en |
| dc.subject | Greece | en |
| dc.subject | Humans | en |
| dc.subject | Keratoconjunctivitis/epidemiology | en |
| dc.subject | Male | en |
| dc.subject | Questionnaires | en |
| dc.subject | *RNA, Small Cytoplasmic | en |
| dc.subject | *Ribonucleoproteins | en |
| dc.subject | Salivary Glands/pathology | en |
| dc.subject | Sjogren's Syndrome/diagnosis/*epidemiology | en |
| dc.subject | Xerostomia/epidemiology | en |
| dc.title | Prevalence of primary Sjogren's syndrome in an elderly population | en |
| heal.abstract | Sixty-two elderly apparently healthy volunteers, inmates of a public nursing home, were examined for evidence of primary Sjogren's syndrome (pSS). Evaluation included a specific questionnaire for subjective xerophthalmia and xerostomia, slit-lamp eye examination after rose Bengal staining. Schirmer's I test, stimulated parotid flow measurement, testing of sera for autoantibodies and labial minor salivary gland biopsy. A greater than or equal to 2+ lip biopsy score on Tarpley's scale was a sine qua non for the diagnosis of Sjogren's syndrome. Labial salivary gland (LSG) biopsy revealed fibrosis and/or fatty infiltration in the majority of the individuals, related to ageing. However, four people had a lip biopsy score of greater than or equal to 2+, which, supplemented by other objective criteria, classified three of them as having pSS. Another four had an LSG biopsy score of 1+, and although they fulfilled other objective criteria, they could not be characterized as pSS. All these individuals were completely asymptomatic, and none of them had anti-Ro(SSA) or anti-La(SSB) autoantibodies. The present study suggests that pSS in elderly people in elderly people is subclinical, benign and relatively common. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/3365531 | - |
| heal.journalName | Br J Rheumatol | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 1988 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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