Optical Properties of Human Melanocytic Nevi In Vivo

dc.contributor.authorZonios, G.en
dc.contributor.authorDimou, A.en
dc.date.accessioned2015-11-24T17:36:59Z
dc.date.available2015-11-24T17:36:59Z
dc.identifier.issn0031-8655-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/14307
dc.rightsDefault Licence-
dc.subjectdiffuse-reflectanceen
dc.subjectstructural disorderen
dc.subjectlight-scatteringen
dc.subjectaction spectraen
dc.subjectskin melaninen
dc.subjecteumelaninen
dc.subjectexplanationen
dc.subjectcoefficienten
dc.subjectabsorptionen
dc.subjecttissueen
dc.titleOptical Properties of Human Melanocytic Nevi In Vivoen
heal.abstractWe present an in vivo study of the optical properties of melanin present in melanocytic nevi of human subjects with Fitzpatrick skin type III (Caucasian descent) using optical spectroscopy. We show that the melanin absorption spectrum exhibits an exponential dependence on wavelength with a decay constant which follows a normal distribution characteristic of a random biological variable. Moreover, we demonstrate lack of correlation among melanin optical properties, melanin concentration and skin light scattering properties, which indicates that the true optical absorption of melanin can be measured free from confounding scattering effects. We also show that the average melanin absorption spectrum in vivo is in very good agreement with a previously reported oxygen photoconsumption action spectrum of melanin. Finally, we provide an overview of the emerging picture of the melanin absorption properties in vivo among various skin types and also among various skin lesions such as melanocytic nevi and melanoma.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primaryDOI 10.1111/j.1751-1097.2008.00436.x-
heal.identifier.secondary<Go to ISI>://000262486800036-
heal.journalNamePhotochemistry and Photobiologyen
heal.journalTypepeer reviewed-
heal.languageen-
heal.publicationDate2009-
heal.publisherWiley-Blackwell Publishingen
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Μηχανικών Επιστήμης Υλικώνel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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