Tamoxifen-induced hypertriglyceridemia in association with diabetes mellitus

dc.contributor.authorMilionis, H. J.en
dc.contributor.authorLiberopoulos, E. N.en
dc.contributor.authorElisaf, M. S.en
dc.date.accessioned2015-11-24T19:43:06Z
dc.date.available2015-11-24T19:43:06Z
dc.identifier.issn1262-3636-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/24723
dc.rightsDefault Licence-
dc.subjectAntineoplastic Agents, Hormonal/adverse effectsen
dc.subjectAntineoplastic Combined Chemotherapy Protocols/therapeutic useen
dc.subjectBlood Glucose/metabolismen
dc.subjectBreast Neoplasms/*drug therapy/surgeryen
dc.subjectCholesterol, HDL/blooden
dc.subject*Diabetes Complicationsen
dc.subjectDiabetes Mellitus/blooden
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectHypertriglyceridemia/*chemically induceden
dc.subjectLipoprotein(a)/blooden
dc.subjectMiddle Ageden
dc.subjectPhenotypeen
dc.subjectTamoxifen/*adverse effectsen
dc.subjectTriglycerides/blooden
dc.titleTamoxifen-induced hypertriglyceridemia in association with diabetes mellitusen
heal.abstractSeveral pharmacological agents are associated with hyperlipidemia. Tamoxifen is an example of a drug-induced increase of serum triglyceride levels. However, there are only scarce reports on how inborn errors in lipid metabolism as well as secondary dyslipidemias, including diabetes mellitus, influence the hypertriglyceridemic effect of tamoxifen. Herein, we describe a case of a breast cancer patient receiving tamoxifen who presented with remarkable hypertriglyceridemia in the context of diabetes mellitus. We also provide a brief review of the relevant literature and discuss the mechanisms underlying the pathogenesis of hypertriglyceridemia related to tamoxifen.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/11353883-
heal.journalNameDiabetes & Metabolismen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2001-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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