Effect of cyproheptadine hydrochloride on ingestive behaviors

dc.contributor.authorKonstandi, M.en
dc.contributor.authorDellia-Sfikaki, A.en
dc.contributor.authorVaronos, D.en
dc.date.accessioned2015-11-24T19:23:00Z
dc.date.available2015-11-24T19:23:00Z
dc.identifier.issn1043-6618-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22224
dc.rightsDefault Licence-
dc.subjectAnimalsen
dc.subjectAppetite Stimulants/*pharmacologyen
dc.subjectCyproheptadine/*pharmacologyen
dc.subjectDrinking Behavior/*drug effects/physiologyen
dc.subjectEstrus/physiologyen
dc.subjectFeeding Behavior/*drug effects/physiologyen
dc.subjectFemaleen
dc.subjectHistamine H1 Antagonists/pharmacologyen
dc.subjectRatsen
dc.subjectRats, Wistaren
dc.subjectSerotonin Antagonists/pharmacologyen
dc.titleEffect of cyproheptadine hydrochloride on ingestive behaviorsen
heal.abstractCyproheptadine (CY) has been used therapeutically as an appetite stimulant at a dose which appears to have antiserotoninergic activity. However, the role which CY may play in appetite regulation remains unclear. This study was designed to examine the effect of CY on ingestive behaviours in female Wistar rats. CY administered orally (0.52 mg kg-1 b.w., dissolved in the daily water) for up to six oestrus cycles did not affect 24 h food intake. On the other hand, CY reduced both 24 h liquid intake and 24 h urine output. Furthermore, 24 h liquid consumption and 24 h urine output, were found to fluctuate according to the oestrus cycle.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1006/phrs.1996.0006-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/8817644-
heal.identifier.secondaryhttp://ac.els-cdn.com/S1043661896900067/1-s2.0-S1043661896900067-main.pdf?_tid=15ea25cd4ec2990754c375cb9bf89dc3&acdnat=1332759515_922101a80d686983f3eb34b9a9ab64d4-
heal.journalNamePharmacol Resen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1996-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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