Antigen-Antibody Interactions Study by 2d-H-1 Nmr - Molecular Recognition between Decapeptide Analogs of the Acetylcholine-Receptor Alpha-67-76 Fragment and the Anti-Achr Antibodies
| dc.contributor.author | Cung, M. T. | en |
| dc.contributor.author | Marraud, M. | en |
| dc.contributor.author | Tsikaris, V. | en |
| dc.contributor.author | Sakarellos, C. | en |
| dc.contributor.author | Papadouli, I. | en |
| dc.contributor.author | Tzartos, S. J. | en |
| dc.date.accessioned | 2015-11-24T16:51:02Z | |
| dc.date.available | 2015-11-24T16:51:02Z | |
| dc.identifier.issn | 0021-7689 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/9677 | |
| dc.rights | Default Licence | - |
| dc.subject | main immunogenic region | en |
| dc.subject | two-dimensional h-1-nmr | en |
| dc.subject | monoclonal-antibodies | en |
| dc.subject | localization | en |
| dc.subject | residues | en |
| dc.title | Antigen-Antibody Interactions Study by 2d-H-1 Nmr - Molecular Recognition between Decapeptide Analogs of the Acetylcholine-Receptor Alpha-67-76 Fragment and the Anti-Achr Antibodies | en |
| heal.abstract | To investigate the conformational role of the alpha-67-76 decapeptide fragment of the Torpedo acetylcholine receptor (AChR), each residue of the WNPADYGGIK sequence was substituted step by step by alanine. The 2D-NMR conformational study of the peptide analogues in the free state was carried out in DMSO. The COSY and transferred NOESY were applied to study the interactions of a monoclonal antibody (mAb6) directed against the main immunogenic region (MIR) of the AChR and five decapeptide analogues from the MIR. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.secondary | <Go to ISI>://A1992HJ07500005 | - |
| heal.journalName | Journal De Chimie Physique Et De Physico-Chimie Biologique | en |
| heal.journalType | peer reviewed | - |
| heal.language | French | - |
| heal.publicationDate | 1992 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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