Platelets and lipoprotein (a): a brief overview of their role in the pathogenesis of atherothrombosis
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Milionis, H. J.
Mikhailidis, D. P.
Winder, A. F.
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peer-reviewed
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Platelets
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The relationship between lipids and the haemostatic mechanisms participating in the evolution of the atherosclerotic plaque have been undergoing extensive investigation for over a century. Circulating lipoproteins can enhance platelet activity. Among these lipid fractions, lipoprotein (a) (Lp(a)), a predictor of atherosclerotic disease, has been proposed as a link between lipids and haemostasis. In this review, we briefly consider lipid-platelet, and particularly Lp(a)-platelet, interactions which may be relevant to the pathogenesis of atherosclerotic disease and its complications.
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http://www.ncbi.nlm.nih.gov/pubmed/16801103
http://informahealthcare.com/doi/abs/10.1080/09537109975906
http://informahealthcare.com/doi/abs/10.1080/09537109975906
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en
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Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής