Provocation of neurocardiogenic syncope during head-up tilt testing in children: comparison between isoproterenol and nitroglycerin
| dc.contributor.author | Vlahos, A. P. | en |
| dc.contributor.author | Tzoufi, M. | en |
| dc.contributor.author | Katsouras, C. S. | en |
| dc.contributor.author | Barka, T. | en |
| dc.contributor.author | Sionti, I. | en |
| dc.contributor.author | Michalis, L. K. | en |
| dc.contributor.author | Siamopoulou, A. | en |
| dc.contributor.author | Kolettis, T. M. | en |
| dc.date.accessioned | 2015-11-24T18:55:47Z | |
| dc.date.available | 2015-11-24T18:55:47Z | |
| dc.identifier.issn | 1098-4275 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/18930 | |
| dc.rights | Default Licence | - |
| dc.subject | Administration, Sublingual | en |
| dc.subject | Child | en |
| dc.subject | Female | en |
| dc.subject | Humans | en |
| dc.subject | Injections, Intravenous | en |
| dc.subject | Isoproterenol/administration & dosage/adverse effects/*diagnostic use | en |
| dc.subject | Male | en |
| dc.subject | Nitroglycerin/administration & dosage/adverse effects/*diagnostic use | en |
| dc.subject | Sensitivity and Specificity | en |
| dc.subject | Syncope, Vasovagal/*diagnosis/etiology | en |
| dc.subject | *Tilt-Table Test | en |
| dc.title | Provocation of neurocardiogenic syncope during head-up tilt testing in children: comparison between isoproterenol and nitroglycerin | en |
| heal.abstract | OBJECTIVE: Although nitroglycerin- and isoproterenol-augmented tilt tests are of equal value in the diagnosis of neurocardiogenic syncope in adults, no data exist in children. We compared the sensitivity and specificity of the 2 tests in a pediatric population. PATIENTS AND METHODS: We studied 85 patients (33 boys; mean age: 11.6 +/- 2.9 years). Of them, 56 had a diagnostic history of neurocardiogenic syncope, whereas 29 served as controls. After a negative passive phase, they were randomly assigned to either intravenous isoproterenol or sublingual nitroglycerin, and tilt was continued for 20 minutes. RESULTS: Sensitivity was 0.78 for the isoproterenol test and 0.79 for the nitroglycerin test, but specificity was significantly higher for isoproterenol test compared with nitroglycerin test. In patients with a positive test, the duration of the recovery period was significantly longer after nitroglycerin (8.4 +/- 2.7 minutes) than after isoproterenol (5.1 +/- 1.6 minutes). CONCLUSIONS: Nitroglycerin- and isoproterenol-augmented tilt tests are associated with equal sensitivity in the diagnosis of neurocardiogenic syncope in children and adolescents. However, nitroglycerin results in more false-positive tests and produces more prolonged vasovagal symptoms. Our data do not support the routine use of nitroglycerin in the evaluation of syncope in this age group. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1542/peds.2006-1862 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/17224456 | - |
| heal.identifier.secondary | http://pediatrics.aappublications.org/content/119/2/e419.full.pdf | - |
| heal.journalName | Pediatrics | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2007 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
Αρχεία
Φάκελος/Πακέτο αδειών
1 - 1 of 1
Φόρτωση...
- Ονομα:
- license.txt
- Μέγεθος:
- 1.74 KB
- Μορφότυπο:
- Item-specific license agreed upon to submission
- Περιγραφή: