Statins: another class of antihypertensive agents?

dc.contributor.authorMilionis, H. J.en
dc.contributor.authorLiberopoulos, E. N.en
dc.contributor.authorAchimastos, A.en
dc.contributor.authorElisaf, M. S.en
dc.contributor.authorMikhailidis, D. P.en
dc.date.accessioned2015-11-24T18:50:36Z
dc.date.available2015-11-24T18:50:36Z
dc.identifier.issn0950-9240-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18111
dc.rightsDefault Licence-
dc.subjectAntihypertensive Agents/*pharmacologyen
dc.subjectBlood Pressure/*drug effectsen
dc.subjectClinical Trials as Topicen
dc.subjectEndothelium, Vascular/drug effectsen
dc.subjectHumansen
dc.subjectHydroxymethylglutaryl-CoA Reductase Inhibitors/*pharmacologyen
dc.subjectHyperlipidemias/*drug therapy/physiopathologyen
dc.subjectHypertension/*drug therapy/physiopathologyen
dc.subjectRenin-Angiotensin System/drug effectsen
dc.subjectRisk Factorsen
dc.titleStatins: another class of antihypertensive agents?en
heal.abstractThe assessment of global cardiovascular risk is an essential step in the management of atherosclerotic disease prevention. Among the risk factors to be addressed are hypertension and hyperlipidaemia; these commonly coexist. A neutral or lipid-friendly antihypertensive agent is probably useful in the presence of lipid abnormalities. Similarly, statins have been shown to decrease cardiovascular risk in hypertensive patients. There is also experimental and clinical evidence that statins have blood pressure (BP)-lowering effects. In this review, we discuss the beneficial effects of statins on BP, and provide an overview of the underlying pathophysiology. We also consider the evidence justifying the use of statins in the management of hypertensive patients.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1038/sj.jhh.1002001-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/16511505-
heal.identifier.secondaryhttp://www.nature.com/jhh/journal/v20/n5/pdf/1002001a.pdf-
heal.journalNameJ Hum Hypertensen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2006-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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