The role of MRI in the evaluation of hip joint disease in clinical subtypes of juvenile idiopathic arthritis

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dc.contributor.authorArgyropoulou, M. I.en
dc.contributor.authorFanis, S. L.en
dc.contributor.authorXenakis, T.en
dc.contributor.authorEfremidis, S. C.en
dc.contributor.authorSiamopoulou, A.en
dc.date.accessioned2015-11-24T19:29:20Z
dc.date.available2015-11-24T19:29:20Z
dc.identifier.issn0007-1285-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22965
dc.rightsDefault Licence-
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectAnalysis of Varianceen
dc.subjectArthritis, Juvenile Rheumatoid/*diagnosisen
dc.subjectChilden
dc.subjectChild, Preschoolen
dc.subjectFemaleen
dc.subject*Hip Jointen
dc.subjectHumansen
dc.subjectMagnetic Resonance Imaging/*methodsen
dc.subjectMaleen
dc.subjectSeverity of Illness Indexen
dc.titleThe role of MRI in the evaluation of hip joint disease in clinical subtypes of juvenile idiopathic arthritisen
heal.abstractThe purpose of this study was to evaluate the role of MRI in the assessment of hip joint involvement in clinical subtypes of juvenile idiopathic arthritis (JIA). 28 patients (mean age 12.5 years) with JIA (oligoarthritis 8, polyarthritis 13, systemic arthritis 7) were examined with T(2) weighted turbo spin echo and T(1) weighted spin echo (plain and contrast enhanced) sequences. The severity of joint involvement was evaluated using an MR grading score: grade 1=no contrast enhancement; grade 2=focal synovial contrast enhancement; grade 3=diffuse synovial contrast enhancement; grade 4=grade 3+diffuse synovial thickening; grade 5=grade 4+villonodular synovial thickening; and grade 6=grade 5+cartilage and subchondral bone erosions. MRI was abnormal in 57.1% of cases (25% of oligoarthritis, 53.8% of polyarthritis and 100% of systemic arthritis). Clinical examination was positive in 32.1% of cases and was associated with higher MR grades (mean 4.6, SD 1.34) compared with a negative clinical examination, which was associated with lower MR grades (mean 1.78, SD 1.13) (p<0.001). Patients with active disease (mean grade 3.9, SD 2) had higher MR grades than those with inactive disease (mean grade 2.1, SD 1.4) (p<0.01). The MR grades were different in the three clinical subtypes: oligoarticular (mean 1.5, SD 1.06); polyarticular (mean 2.38, SD 1.55); and systemic (mean 4.85, SD 1.21) (F:12.3, p<0.001), with a significant difference between systemic arthritis and oligoarthritis, and between systemic arthritis and polyarthritis (p<0.001). MRI of the hip might be considered for inclusion in the study protocol of patients with JIA since it reveals joint involvement at early stages and provides a detailed evaluation of the extent of joint disease.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/11932215-
heal.identifier.secondaryhttp://bjr.birjournals.org/content/75/891/229.full.pdf-
heal.journalNameBr J Radiolen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2002-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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