LC-NMR coupling technology: recent advancements and applications in natural products analysis

dc.contributor.authorExarchou, V.en
dc.contributor.authorKrucker, M.en
dc.contributor.authorvan Beek, T. A.en
dc.contributor.authorVervoort, J.en
dc.contributor.authorGerothanassis, I. P.en
dc.contributor.authorAlbert, K.en
dc.date.accessioned2015-11-24T16:40:58Z
dc.date.available2015-11-24T16:40:58Z
dc.identifier.issn0749-1581-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/8343
dc.rightsDefault Licence-
dc.subjectlc-nmren
dc.subjectlc-spe-nmren
dc.subjecthyphenationen
dc.subjectnatural productsen
dc.subjectnuclear-magnetic-resonanceen
dc.subjectperformance liquid-chromatographyen
dc.subjectsolid-phase extractionen
dc.subjecthigh-resolution nmren
dc.subjecttandem mass-spectrometryen
dc.subjectcrude plant-extractsen
dc.subjectdad-spe-nmren
dc.subjecthplc-nmren
dc.subjectnaphthylisoquinoline alkaloidsen
dc.subjectsolvent-suppressionen
dc.titleLC-NMR coupling technology: recent advancements and applications in natural products analysisen
heal.abstractAn overview of recent advances in nuclear magnetic resonance (NMR) coupled with separation technologies and their application in natural product analysis is given and discussed. The different modes of LC-NMR operation are described, as well as how technical improvements assist in establishing LC-NMR as an important tool in the analysis of plant-derived compounds. On-flow, stopped-flow and loop-storage procedures are mentioned, together with the new LC-SPE-NMR configuration. The implementation of mass spectrometry in LC-NMR is also useful on account of the molecular weight and fragmentation information that it provides, especially when new plant species are studied. Cryogenic technology and capillary LC-NMR are the other important recent developments. Since the plant kingdom is endless in producing potential drug candidates, development and optimization of LC-NMR techniques convert the study of natural products to a less-time-consuming task, speeding up identification. Copyright (c) 2005 John Wiley & Sons, Ltd.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primaryDoi 10.1002/Mrc.1632-
heal.identifier.secondary<Go to ISI>://000231206200003-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1002/mrc.1632/asset/1632_ftp.pdf?v=1&t=hmn3iwdi&s=52f8f63852067c39ddf87875914a2a3e3b475e66-
heal.journalNameMagnetic Resonance in Chemistryen
heal.journalTypepeer reviewed-
heal.languageen-
heal.publicationDate2005-
heal.publisherWiley-Blackwellen
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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